Interaction between macrophages and ferroptosis

• Published in: Cell death & disease Vol. 13; no. 4; pp. 355 - 10
• Main Authors: Yang, Yan, Wang, Yu, Guo, Lin, Gao, Wen, Tang, Ting-Li, Yan, Miao
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 16.04.2022; Springer Nature B.V; Nature Publishing Group
• Subjects: 631/250/127; 631/250/1933; 631/67/1059/2325; Amino acids; Amino Acids - metabolism; Antibodies; Biochemistry; Biomedical and Life Sciences; Cancer; Cell Biology; Cell Culture; Cell death; Cytokines; Cytokines - metabolism; Ferroptosis; Homeostasis; Humans; Immunology; Inflammation; Inflammation - metabolism; Iron; Iron - metabolism; Life Sciences; Lipid Peroxidation; Lipid Peroxides - metabolism; Lipids; Liver diseases; Macrophages; Macrophages - metabolism; Neoplasms - genetics; Neoplasms - metabolism; Neurological diseases; Phagocytes; Phagocytosis; Polarization; Reactive Oxygen Species - metabolism; Review; Review Article; Tumor Microenvironment; Tumors

Ferroptosis, a newly discovered iron-dependent cell death pathway, is characterized by lipid peroxidation and GSH depletion mediated by iron metabolism and is morphologically, biologically and genetically different from other programmed cell deaths. Besides, ferroptosis is usually found accompanied...