Cytoplasmic DAXX drives SQSTM1/p62 phase condensation to activate Nrf2-mediated stress response - Yang, Yi; Willis, Thea L.; Button, Robert W.; Strang, Conor J.; Fu, Yuhua; Wen, Xue; Grayson, Portia R. C.; Evans, Tracey; Sipthorpe, Rebecca J.; Roberts, Sheridan L.; Hu, Bing; Zhang, Jianke; et al. (Nature communications, 2019)
Keywords: 13; 13/1; 13/106; 13/109; 13/2; 13/31; 13/51; 13/89; 14; 14/19; 631/45/470; 631/57/2269; 631/57/2272; 631/80/39/2346; 82/29; 82/51; 82/80; 82/83; Adaptor Proteins, Signal Transducing - genetics; Adaptor Proteins, Signal Transducing - metabolism; Animals; Autophagy; Autophagy - physiology; Cargo compartments; Cell Line; Co-Repressor Proteins; Condensation; Cytoplasm - metabolism; Daxx protein; Drosophila; Female; Gene Knockdown Techniques; HEK293 Cells; HeLa Cells; Humanities and Social Sciences; Humans; Intracellular; Kelch-Like ECH-Associated Protein 1 - metabolism; Liquid phases; Male; Mice; Molecular Chaperones; multidisciplinary; NF-E2-Related Factor 2 - metabolism; Nuclear Proteins - genetics; Nuclear Proteins - metabolism; Phagocytosis; Phase separation; Protein Binding; Protein Folding; Protein Interaction Domains and Motifs; Proteins; Quality control; RNA-Binding Proteins - metabolism; Science; Science (multidisciplinary); Sequestosome-1 Protein - metabolism; Stress response; Yeast