Induction of ferroptosis in human nasopharyngeal cancer cells by cucurbitacin B: molecular mechanism and therapeutic potential - Huang, Shuai; Cao, Bihui; Zhang, Jinling; Feng, Yunfei; Wang, Lu; Chen, Xiaopei; Su, Hang; Liao, Shengrong; Liu, Jinggong; Yan, Jun; Liang, Baoxia (Cell death & disease, 2021)
Keywords: 13/1; 13/2; 13/31; 14/19; 14/28; 631/67/1059/153; 631/67/2327; Animals; Antibodies; Antifungal agents; Antineoplastic Agents, Phytogenic - pharmacology; Apoptosis; Biochemistry; Biomedical and Life Sciences; Cell Biology; Cell Culture; Cell cycle; Cell migration; Cell Movement - drug effects; Cytology; Cytotoxicity; Female; Ferroptosis; Ferroptosis - drug effects; G2 Phase Cell Cycle Checkpoints - drug effects; Glutathione; Hep G2 Cells; Humans; Immunology; Life Sciences; Lipid peroxidation; Lipid Peroxidation - drug effects; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Molecular modelling; Nasopharyngeal carcinoma; Nasopharyngeal Carcinoma - drug therapy; Nasopharyngeal Carcinoma - genetics; Nasopharyngeal Carcinoma - metabolism; Nasopharyngeal Carcinoma - pathology; Nasopharyngeal Neoplasms - drug therapy; Nasopharyngeal Neoplasms - genetics; Nasopharyngeal Neoplasms - metabolism; Nasopharyngeal Neoplasms - pathology; Natural products; Neoplasm Invasiveness; Phospholipid Hydroperoxide Glutathione Peroxidase - genetics; Phospholipid Hydroperoxide Glutathione Peroxidase - metabolism; Throat cancer; Transmission electron microscopy; Triterpenes - pharmacology; Tumor Burden - drug effects; Tumors; Ultrastructure; Xenograft Model Antitumor Assays