Development of a functional composite for the evaluation of spinal and bulbar muscular atrophy

• Published in: Scientific reports Vol. 12; no. 1; pp. 17443 - 8
• Main Authors: Inagaki, Tomonori, Hashizume, Atsushi, Hijikata, Yasuhiro, Yamada, Shinichiro, Ito, Daisuke, Kishimoto, Yoshiyuki, Torii, Ryota, Sato, Hiroyuki, Hirakawa, Akihiro, Katsuno, Masahisa
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 19.10.2022; Nature Publishing Group; Nature Portfolio
• Subjects: 692/617; 692/617/375/364; Age; Androgens; Atrophy; Bulbo-Spinal Atrophy, X-Linked - diagnosis; Bulbo-Spinal Atrophy, X-Linked - genetics; Clinical trials; Consent; Disease; Disease Progression; Hospitals; Humanities and Social Sciences; Humans; multidisciplinary; Muscle Strength; Muscular Atrophy, Spinal - diagnosis; Neuromuscular diseases; Patients; Pressure; Respiration; Science; Science (multidisciplinary); Spinal and bulbar muscular atrophy; Tongue; University graduates; Walking
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-022-22322-w

This study aimed to develop a functional measurement that combines quantitative motor evaluation index of various body regions in patients with spinal and bulbar muscular atrophy (SBMA). We assessed subjects with SBMA and healthy controls with quantitative muscle strength measurements and functional...