Targeting ubiquitin signaling for cancer immunotherapy

• Published in: Signal transduction and targeted therapy Vol. 6; no. 1; pp. 16 - 15
• Main Authors: Zhou, Xiaofei, Sun, Shao-Cong
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 13.01.2021; Nature Publishing Group
• Subjects: 631/250/251; 631/250/580; Cancer; Cancer Research; Cell Biology; Deubiquitinating Enzymes - immunology; Humans; Immune Checkpoint Inhibitors - therapeutic use; Immunotherapy; Internal Medicine; Medicine; Medicine & Public Health; Neoplasm Proteins - immunology; Neoplasms - immunology; Neoplasms - therapy; Oncology; Pathology; Review; Review Article; Ubiquitin - immunology; Ubiquitin-Protein Ligases - immunology; Ubiquitination - immunology

Cancer immunotherapy has become an attractive approach of cancer treatment with tremendous success in treating various advanced malignancies. The development and clinical application of immune checkpoint inhibitors represent one of the most extraordinary accomplishments in cancer immunotherapy. In a...