SUMOylation of VEGFR2 regulates its intracellular trafficking and pathological angiogenesis - Zhou, Huanjiao Jenny; Xu, Zhe; Wang, Zongren; Zhang, Haifeng; Zhuang, Zhen W.; Simons, Michael; Min, Wang (Nature communications, 2018)
Keywords: 13/109; 13/95; 38/23; 45/23; 45/70; 45/77; 631/337/458/538; 631/443/592/16; 631/80/2023/2022; 96/100; 96/2; 96/31; Acetylation; Angiogenesis; Animals; Clonal deletion; Cornea; Cornea - blood supply; Cysteine Endopeptidases - metabolism; Diabetes; Diabetes mellitus; Diabetes Mellitus - pathology; Endopeptidases; Endopeptidases - metabolism; Endothelial cells; Gene Deletion; Gene Knock-In Techniques; Gene Silencing; Golgi apparatus; Golgi Apparatus - drug effects; Golgi Apparatus - metabolism; Human Umbilical Vein Endothelial Cells - drug effects; Human Umbilical Vein Endothelial Cells - metabolism; Humanities and Social Sciences; Humans; Intracellular Space - metabolism; Ischemia; Lysine; Male; Mice, Inbred C57BL; Mice, Knockout; multidisciplinary; Neovascularization, Pathologic - metabolism; Post-translation; Protein Transport; Retina; Retina - pathology; Science; Science (multidisciplinary); Signal Transduction - drug effects; Signaling; SUMO protein; SUMO-1 Protein - metabolism; Sumoylation; Therapeutic applications; Ubiquitination; Vascular endothelial growth factor; Vascular Endothelial Growth Factor A - pharmacology; Vascular Endothelial Growth Factor Receptor-2 - chemistry; Vascular Endothelial Growth Factor Receptor-2 - metabolism