Inhibiting HMGB1-RAGE axis prevents pro-inflammatory macrophages/microglia polarization and affords neuroprotection after spinal cord injury - Fan, Hong; Tang, Hai-Bin; Chen, Zhe; Wang, Hu-Qing; Zhang, Lei; Jiang, Yu; Li, Tao; Yang, Cai-Feng; Wang, Xiao-Ya; Li, Xia; Wu, Sheng-Xi; Zhang, Gui-Lian (Journal of neuroinflammation, 2020)
Keywords: Advanced glycosylation end products; Antibodies; Astrocytes; Brain damage; Complications and side effects; Demyelination; DNA binding proteins; Enzyme-linked immunosorbent assay; Gene expression; Glial fibrillary acidic protein; Glycosylation; Glycyrrhizin; Health aspects; High mobility group proteins; HMGB1; HMGB1 protein; Immunohistochemistry; Inflammation; Kinases; Macrophages; Macrophages/microglia; Microglia; Myelin; Necroptosis; Neuroprotection; NF-κB protein; Phenotypes; Physiological aspects; Polarization; Polymerase chain reaction; Prevention; Proteins; RAGE; Recovery of function; Risk factors; Spinal cord injuries; Spinal cord injury; Trauma; China