Ketogenic diet for human diseases: the underlying mechanisms and potential for clinical implementations

• Published in: Signal transduction and targeted therapy Vol. 7; no. 1; pp. 11 - 21
• Main Authors: Zhu, Huiyuan, Bi, Dexi, Zhang, Youhua, Kong, Cheng, Du, Jiahao, Wu, Xiawei, Wei, Qing, Qin, Huanlong
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 17.01.2022; Nature Publishing Group
• Subjects: 692/699/317; 692/700/1538; Cancer Research; Cell Biology; Clinical trials; Diet; Diet, Ketogenic; Drug Resistant Epilepsy - diet therapy; Epilepsy; High fat diet; High protein diet; Humans; Internal Medicine; Ketogenesis; Ketones; Low carbohydrate diet; Low fat diet; Low protein diet; Medicine; Medicine & Public Health; Neoplasms - diet therapy; Nutrient deficiency; Obesity - diet therapy; Oncology; Pathology; Randomized Controlled Trials as Topic; Review; Review Article

The ketogenic diet (KD) is a high-fat, adequate-protein, and very-low-carbohydrate diet regimen that mimics the metabolism of the fasting state to induce the production of ketone bodies. The KD has long been established as a remarkably successful dietary approach for the treatment of intractable epi...