The Comet Assay as a Tool in Human Biomonitoring Studies of Environmental and Occupational Exposure to Chemicals—A Systematic Scoping Review

• Published in: Toxics (Basel) Vol. 12; no. 4; p. 270
• Main Authors: Ladeira, Carina, Møller, Peter, Giovannelli, Lisa, Gajski, Goran, Haveric, Anja, Bankoglu, Ezgi Eyluel, Azqueta, Amaya, Gerić, Marko, Stopper, Helga, Cabêda, José, Tonin, Fernanda S., Collins, Andrew
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.04.2024; MDPI
• Subjects: Air pollution; anaesthetics; Analysis; Anesthetics; Antineoplastic drugs; Assaying; Bioassays; Biological assay; Biological monitoring; Biomarkers; Biomonitoring; Carcinogens; Chemicals; Comet assay; Damage assessment; Damage detection; Damage prevention; Deoxyribonucleic acid; DNA; DNA damage; Drugs; Environmental studies; Epidemiology; Exposure; Heavy metals; human biomonitoring; Human populations; Human subjects; Methods; Mutagens; Occupational exposure; Occupational health; Outdoor air quality; Pesticides; Review; Solvents; Toxicity testing; Portugal; comet assay; exposure; heavy metals; pesticides; antineoplastic drugs; air pollution; solvents; anaesthetics; human biomonitoring

Biomonitoring of human populations exposed to chemical substances that can act as potential mutagens or carcinogens, may enable the detection of damage and early disease prevention. In recent years, the comet assay has become an important tool for assessing DNA damage, both in environmental and occu...