Inhibition of microbiota-dependent TMAO production attenuates chronic kidney disease in mice - Zhang, Wenchao; Miikeda, Aika; Zuckerman, Jonathan; Jia, Xun; Charugundla, Sarada; Zhou, Zhiqiang; Kaczor-Urbanowicz, Karolina Elżbieta; Magyar, Clara; Guo, Fangfei; Wang, Zeneng; Pellegrini, Matteo; Hazen, Stanley L.; et al. (Scientific reports, 2021)
Keywords: 631/337; 631/80; 692/4019; 692/4022; 692/699; Adenine; Adenine - administration & dosage; Adenine - adverse effects; Albuminuria - etiology; Animal models; Animals; Aorta; Apolipoprotein E; Arteriosclerosis; Cardiomegaly - etiology; Cardiomegaly - prevention & control; Cardiovascular disease; Cardiovascular diseases; Choline; Choline - administration & dosage; Choline - adverse effects; Choline - analogs & derivatives; Choline - pharmacology; Creatinine; Cystatin C; Dietary supplements; Disease Models, Animal; Female; Fibroblast Growth Factor-23; Fibrosis; Gastrointestinal Microbiome - physiology; Humanities and Social Sciences; Hypertrophy; Inflammation; Kidney - pathology; Kidney diseases; Kidneys; Metabolites; Methylamines - administration & dosage; Methylamines - adverse effects; Methylamines - metabolism; Mice; Microbiota; multidisciplinary; Plasma levels; Renal Insufficiency, Chronic - etiology; Renal Insufficiency, Chronic - pathology; Renal Insufficiency, Chronic - prevention & control; Science; Science (multidisciplinary); Trimethylamine