Postzygotic HRAS and KRAS mutations cause nevus sebaceous and Schimmelpenning syndrome - Groesser, Leopold; Herschberger, Eva; Ruetten, Arno; Ruivenkamp, Claudia; Lopriore, Enrico; Zutt, Markus; Langmann, Thomas; Singer, Sebastian; Klingseisen, Laura; Schneider-Brachert, Wulf; Toll, Agusti; Real, Francisco X; et al. (Nature genetics, 2012)
Keywords: 631/208/2489/144; 631/208/727/2000; 631/67/68; 692/699/375; Abnormalities, Multiple - genetics; Adolescent; Adult; Aged; Agriculture; Animal Genetics and Genomics; Biological and medical sciences; Biomedical and Life Sciences; Biomedicine; Cancer Research; Cell culture; Cell physiology; Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes; Child; Child, Preschool; Dermatology; Female; Fundamental and applied biological sciences. Psychology; Gene Function; Gene mutations; Genes; Genetic aspects; Genetics of eukaryotes. Biological and molecular evolution; Health aspects; Human Genetics; Humans; letter; Male; Medical sciences; Mitogen-Activated Protein Kinase Kinases - genetics; Molecular and cellular biology; Mosaicism; Mutation; Nervous system diseases; Nevus - genetics; Nevus, Sebaceous of Jadassohn - genetics; Pathogenesis; Phosphatidylinositol 3-Kinases - genetics; Phosphorylation; Proto-Oncogene Proteins - genetics; Proto-Oncogene Proteins c-akt - genetics; Proto-Oncogene Proteins p21(ras) - genetics; ras Proteins - genetics; Risk factors; Signal Transduction; Studies; Tumors of the skin and soft tissue. Premalignant lesions; Twins; Young Adult; Germany; Skin disease; Benign neoplasm; Mutation; Onc gene; Sebaceous nevus; Syndrome