Stereospecific Si-C coupling and remote control of axial chirality by enantioselective palladium-catalyzed hydrosilylation of maleimides

• Published in: Nature communications Vol. 11; no. 1; pp. 2904 - 9
• Main Authors: Gu, Xing-Wei, Sun, Yu-Li, Xie, Jia-Le, Wang, Xing-Ben, Xu, Zheng, Yin, Guan-Wu, Li, Li, Yang, Ke-Fang, Xu, Li-Wen
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 09.06.2020; Nature Publishing Group; Nature Portfolio
• Subjects: 119/118; 140/131; 49/98; 631/154/309/2132/605; 639/638/549/972; 639/638/911/406/938; Activated carbon; Alkenes; Asymmetry; Carbon; Carbonyl compounds; Carbonyls; Catalysts; Chemical bonds; Chirality; Construction; Coupling; Enantiomers; Humanities and Social Sciences; Hydrosilylation; Isomerization; multidisciplinary; Organic chemistry; Organosilicon compounds; Palladium; Reduction; Remote control; Science; Science (multidisciplinary); Stereoselectivity; Succinimides

Hydrosilylation of unsaturated carbon-carbon bonds with hydrosilanes is a very important process to access organosilicon compounds and ranks as one of the most fundamental reactions in organic chemistry. However, catalytic asymmetric hydrosilylation of activated alkenes and internal alkenes has prov...