Influenza A viruses are transmitted via the air from the nasal respiratory epithelium of ferrets

• Published in: Nature communications Vol. 11; no. 1; pp. 766 - 11
• Main Authors: Richard, Mathilde, van den Brand, Judith M. A., Bestebroer, Theo M., Lexmond, Pascal, de Meulder, Dennis, Fouchier, Ron A. M., Lowen, Anice C., Herfst, Sander
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 07.02.2020; Nature Publishing Group; Nature Portfolio
• Subjects: 13; 13/106; 13/109; 13/51; 38/70; 45/23; 45/77; 45/88; 45/90; 631/326/596/1578; 631/326/596/2563; 64; Air; Animals; Disease transmission; Dogs; Epithelium; Female; Ferrets - virology; Genotypes; Humanities and Social Sciences; Humans; Influenza; Influenza A; Influenza A virus - genetics; Influenza A virus - pathogenicity; Influenza A virus - physiology; Inoculation; Madin Darby Canine Kidney Cells; multidisciplinary; Mustela; Nasal Mucosa - virology; Nose; Orthomyxoviridae Infections - transmission; Orthomyxoviridae Infections - veterinary; Replication; Respiratory tract; Respiratory tract diseases; Science; Science (multidisciplinary); Trachea; Viral Tropism; Viruses

Human influenza A viruses are known to be transmitted via the air from person to person. It is unknown from which anatomical site of the respiratory tract influenza A virus transmission occurs. Here, pairs of genetically tagged and untagged influenza A/H1N1, A/H3N2 and A/H5N1 viruses that are transm...