Divergent synthesis of N-heterocycles via controllable cyclization of azido-diynes catalyzed by copper and gold

• Published in: Nature communications Vol. 8; no. 1; pp. 1748 - 9
• Main Authors: Shen, Wen-Bo, Sun, Qing, Li, Long, Liu, Xin, Zhou, Bo, Yan, Juan-Zhu, Lu, Xin, Ye, Long-Wu
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 23.11.2017; Nature Publishing Group; Nature Portfolio
• Subjects: 639/638/403/933; 639/638/403/934; Alkynes; Carbenes; Cascade chemical reactions; Catalysis; Catalysts; Chemical engineering; Chemical reactions; Chemical synthesis; Collaboration; Copper; Gold; Humanities and Social Sciences; Indoles; Laboratories; multidisciplinary; Optimization; Oxidation; Oxidizing agents; Physical chemistry; Science; Science (multidisciplinary); Stability

Gold-catalyzed intermolecular alkyne oxidation by an N–O bond oxidant has proven to be a powerful method in organic synthesis during the past decade, because this approach would enable readily available alkynes as precursors in generating α-oxo gold carbenes. Among those, gold-catalyzed oxidative cy...