Clinical impact of Hypofractionated carbon ion radiotherapy on locally advanced hepatocellular carcinoma

• Published in: Radiation oncology (London, England) Vol. 15; no. 1; pp. 1 - 8
• Main Authors: Shiba, Shintaro, Shibuya, Kei, Okamoto, Masahiko, Okazaki, Shohei, Komatsu, Shuichiro, Kubota, Yoshiki, Nakano, Takashi, Ohno, Tatsuya
• Format: Journal Article
• Language: English
• Published: London BioMed Central Ltd 14.08.2020; BioMed Central; BMC
• Subjects: Biological effects; Cancer therapies; Carbon; Carbon ion radiotherapy; Care and treatment; Chemotherapy; Clinical outcomes; Development and progression; Gastrointestinal tract; Health services; Hepatic vein; Hepatocellular carcinoma; Hypofractionation; Ion beams; Liver cancer; Liver diseases; Magnetic resonance imaging; Medical prognosis; Metastasis; Methods; Patient outcomes; Patient positioning; Patients; Portal vein; Radiation; Radiation effects; Radiation therapy; Radiotherapy; Relative biological effectiveness (RBE); Survival; Toxicity; Ultrasonic imaging; Vascular invasion; Veins & arteries; X-rays; Japan

Abstract Background Hepatocellular carcinoma (HCC) involving a major branch of the portal or hepatic vein is in a locally advanced stage and remains difficult to cure. This study aimed to evaluate the clinical effects of carbon ion radiotherapy (C-ion RT) in locally advanced HCC (LAHCC). Methods The...