Efficacy of systemic antibiotics in nonsurgical periodontal therapy for diabetic subjects: a systematic review and meta-analysis

• Published in: International dental journal Vol. 68; no. 4; pp. 207 - 220
• Main Authors: Souto, Maria Luisa S., Rovai, Emanuel S., Ganhito, Juliana A., Holzhausen, Marinella, Chambrone, Leandro, Pannuti, Cláudio M.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.08.2018; Elsevier Limited; Elsevier
• Subjects: Amoxicillin; Amoxicillin - therapeutic use; Anti-Bacterial Agents - therapeutic use; anti-infective agents; Antibiotics; Clinical trials; Concise Review; Dental Scaling; Dentistry; Diabetes; Diabetes mellitus; Diabetes Mellitus - drug therapy; Doxycycline - therapeutic use; Drug Therapy, Combination; Gingival index; Gum disease; Humans; Meta-analysis; Metronidazole; Metronidazole - therapeutic use; Patients; periodontal diseases; Periodontal Diseases - therapy; Periodontal Pocket; Periodontitis; root planing; Systematic review; anti-infective agents; periodontal diseases; systematic review; Diabetes mellitus; root planing

Objectives: To evaluate the effects of systemic antibiotics as adjuncts to nonsurgical periodontal treatment (NSPT), as opposed to using NSPT alone, on periodontal clinical parameters of diabetic patients with periodontitis. Materials and methods: Randomised controlled trials with a follow-up of 3 m...