Sedentary behavior as a risk factor for cognitive decline: A focus on the influence of glycemic control in brain health

• Published in: Alzheimer's & dementia : translational research & clinical interventions Vol. 3; no. 3; pp. 291 - 300
• Main Authors: Wheeler, Michael J, Dempsey, Paddy C, Grace, Megan S, Ellis, Kathryn A, Gardiner, Paul A, Green, Daniel J, Dunstan, David W
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.09.2017; John Wiley & Sons, Inc; Elsevier
• Subjects: Alzheimer's disease; Apoptosis; Brain research; Breaks in sedentary time; Chronic illnesses; Cognitive function; Dementia; Diabetes; Energy; Exercise; Glucose; Glucose metabolism; Hyperglycemia; Hypoglycemia; Insulin resistance; Investigations; Light-intensity activity; Metabolism; Neurology; Neuropathology; Older people; Other; Physical activity; Public health; Sedentary behavior; Sitting; United States > US; Glucose metabolism; Sedentary behavior; Exercise; Physical activity; Sitting; Light-intensity activity; Breaks in sedentary time; Diabetes; Cognitive function; Alzheimer's disease; Dementia

Abstract Cognitive decline leading to dementia represents a global health burden. In the absence of targeted pharmacotherapy, lifestyle approaches remain the best option for slowing the onset of dementia. However, older adults spend very little time doing moderate to vigorous exercise and spend most...