Effects of N‐acetylcysteine on oxidative stress biomarkers, depression, and anxiety symptoms in patients with multiple sclerosis

• Published in: Neuropsychopharmacology reports Vol. 43; no. 3; pp. 382 - 390
• Main Authors: Khalatbari Mohseni, Golsa, Hosseini, Seyed Ahmad, Majdinasab, Nastaran, Cheraghian, Bahman
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.09.2023; John Wiley and Sons Inc; Wiley
• Subjects: antioxidant; Antioxidants; Anxiety; Biomarkers; Blood; Brain research; Chronic illnesses; depression; Disease; Drug dosages; Glutathione; Lipid peroxidation; Mental depression; Multiple sclerosis; Neurological disorders; N‐acetylcysteine; Obsessive compulsive disorder; Original; Oxidative stress; Iran; Switzerland; anxiety; antioxidant; glutathione; multiple sclerosis; depression; oxidative stress; N-acetylcysteine

Aim N‐acetylcysteine (NAC), a thiol‐containing antioxidant and glutathione (GSH) precursor, attenuates oxidative stress, and possibly improves psychiatric disorders. This study aimed to evaluate the effects of oral NAC on oxidative stress, depression, and anxiety symptoms in patients with multiple s...