Regulation of Spatiotemporal Patterns by Biological Variability: General Principles and Applications to Dictyostelium discoideum

• Published in: PLoS computational biology Vol. 11; no. 11; p. e1004367
• Main Authors: Grace, Miriam, Hütt, Marc-Thorsten
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 01.11.2015; Public Library of Science (PLoS)
• Subjects: Algorithms; Biology; Colleges & universities; Colonies & territories; Dictyostelium; Dictyostelium - physiology; Gene expression; Genetic aspects; Models, Biological; Morphogenesis; Physics; Principles; Review; Signal Transduction - physiology; Spatio-Temporal Analysis; Systems Biology - methods; United States

Spatiotemporal patterns often emerge from local interactions in a self-organizing fashion. In biology, the resulting patterns are also subject to the influence of the systematic differences between the system's constituents (biological variability). This regulation of spatiotemporal patterns by...