Wild-Type Monomeric α-Synuclein Can Impair Vesicle Endocytosis and Synaptic Fidelity via Tubulin Polymerization at the Calyx of Held
α-Synuclein is a presynaptic protein the function of which has yet to be identified, but its neuronal content increases in patients of synucleinopathies including Parkinson's disease. Chronic overexpression of α-synuclein reportedly expresses various phenotypes of synaptic dysfunction, but the...
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Published in | The Journal of neuroscience Vol. 37; no. 25; pp. 6043 - 6052 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Society for Neuroscience
21.06.2017
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Subjects | |
Online Access | Get full text |
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