Wild-Type Monomeric α-Synuclein Can Impair Vesicle Endocytosis and Synaptic Fidelity via Tubulin Polymerization at the Calyx of Held

α-Synuclein is a presynaptic protein the function of which has yet to be identified, but its neuronal content increases in patients of synucleinopathies including Parkinson's disease. Chronic overexpression of α-synuclein reportedly expresses various phenotypes of synaptic dysfunction, but the...

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Published inThe Journal of neuroscience Vol. 37; no. 25; pp. 6043 - 6052
Main Authors Eguchi, Kohgaku, Taoufiq, Zacharie, Thorn-Seshold, Oliver, Trauner, Dirk, Hasegawa, Masato, Takahashi, Tomoyuki
Format Journal Article
LanguageEnglish
Published United States Society for Neuroscience 21.06.2017
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