Antipsychotics for delirium in the general hospital setting in consecutive 2453 inpatients: a prospective observational study

• Published in: International journal of geriatric psychiatry Vol. 29; no. 3; pp. 253 - 262
• Main Authors: Hatta, Kotaro, Kishi, Yasuhiro, Wada, Ken, Odawara, Toshinari, Takeuchi, Takashi, Shiganami, Takafumi, Tsuchida, Kazuo, Oshima, Yoshio, Uchimura, Naohisa, Akaho, Rie, Watanabe, Akira, Taira, Toshihiro, Nishimura, Katsuji, Hashimoto, Naoko, Usui, Chie, Nakamura, Hiroyuki
• Format: Journal Article
• Language: English
• Published: Hove Blackwell Publishing Ltd 01.03.2014; Psychology Press; Wiley Subscription Services, Inc; BlackWell Publishing Ltd
• Subjects: adverse event; Aged; Aged, 80 and over; antipsychotic; Antipsychotic Agents - adverse effects; Antipsychotic Agents - therapeutic use; aripiprazole; aspiration pneumonia; Biological and medical sciences; Cardiovascular Diseases - chemically induced; Delirium; Delirium - drug therapy; Dementia; Drug dosages; Female; Geriatric psychiatry; haloperidol; Hospitals, General - statistics & numerical data; Humans; Male; Medical sciences; Neuropharmacology; olanzapine; Older people; perospirone; Pharmacology. Drug treatments; Pneumonia, Aspiration - chemically induced; Prospective Studies; Psycholeptics: tranquillizer, neuroleptic; Psychology. Psychoanalysis. Psychiatry; Psychopharmacology; Psychotropic drugs; quetiapine; Risk assessment; risperidone; Venous Thromboembolism - chemically induced; Wounds and Injuries - chemically induced; Asia; Japan; Delirium; Social environment; Partial agonist; Dibenzodiazepine derivatives; Atypical antipsychotic; Neuroleptic; Psychotropic; Toxicity; Mental health; Quinolinone derivatives; Pharmacotherapy; aspiration pneumonia; Serotonine receptor; Haloperidol; olanzapine; 5-HT1A Serotonine receptor; Complication; antipsychotic; Perospirone; Dibenzothiazepine derivatives; Risperidone; Benzisoxazole derivatives; Mental confusion; Quetiapine; Public health; Human; 5-HT2A serotonin receptor; Observational study; General hospital; Dopamine antagonist; Serotonin antagonist; Treatment efficiency; adverse event; Butyrophenone derivatives; Pharmacovigilance; Thienobenzodiazepine derivatives; Recommendation; Organic mental disorder; D2 Dopamine receptor; Treatment; Follow up study; Risk factor; aripiprazole; Elderly; haloperidol; perospirone; risperidone; quetiapine; delirium

Objective Attention to risk of antipsychotics for older patients with delirium has been paid. A clinical question was whether risk of antipsychotics for older patients with delirium would exceed efficacy of those even in the general hospital setting. Methods A prospective observational study proceed...