Early Impact of Fontan Operation on Enteric Protein Loss

• Published in: The Annals of thoracic surgery Vol. 101; no. 3; pp. 1025 - 1030
• Main Authors: Patel, Jyoti K., MD, Loomes, Kathleen M., MD, Goldberg, David J., MD, Mercer-Rosa, Laura, MD, MSCE, Dodds, Kathryn, CRNP, Rychik, Jack, MD
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 01.03.2016
• Subjects: alpha 1-Antitrypsin - metabolism; Cardiothoracic Surgery; Child, Preschool; Feces - chemistry; Female; Follow-Up Studies; Fontan Procedure - adverse effects; Heart Defects, Congenital - surgery; Humans; Male; Mesenteric Artery, Superior - diagnostic imaging; Mesenteric Artery, Superior - physiopathology; Postoperative Complications; Prognosis; Prospective Studies; Protein-Losing Enteropathies - diagnostic imaging; Protein-Losing Enteropathies - etiology; Protein-Losing Enteropathies - physiopathology; Surgery; Time Factors; Ultrasonography, Doppler

Background Protein-losing enteropathy (PLE) is a challenging complication after a Fontan operation. Subclinical enteric protein loss may precede development of overt PLE. We evaluated the acute effects of Fontan circulation on enteric protein loss and mesenteric vascular resistance. Methods A prospe...