Autopsy analyses in acute exacerbation of idiopathic pulmonary fibrosis

• Published in: Respiratory research Vol. 15; no. 1; p. 109
• Main Authors: Oda, Keishi, Ishimoto, Hiroshi, Yamada, Sohsuke, Kushima, Hisako, Ishii, Hiroshi, Imanaga, Tomotoshi, Harada, Tatsuhiko, Ishimatsu, Yuji, Matsumoto, Nobuhiro, Naito, Keisuke, Yatera, Kazuhiro, Nakazato, Masamitsu, Kadota, Jun-ichi, Watanabe, Kentaro, Kohno, Shigeru, Mukae, Hiroshi
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 01.09.2014; BioMed Central
• Subjects: Adrenal Cortex Hormones - administration & dosage; Adrenal Cortex Hormones - adverse effects; Aged; Aged, 80 and over; Analysis; Autopsy; Bacterial pneumonia; Biopsy; Care and treatment; Cause of Death; Comorbidity; Complications and side effects; Cytomegalovirus; Development and progression; Diagnosis; Disease Progression; Female; Health aspects; Humans; Idiopathic Pulmonary Fibrosis - complications; Idiopathic Pulmonary Fibrosis - drug therapy; Idiopathic Pulmonary Fibrosis - mortality; Idiopathic Pulmonary Fibrosis - pathology; Japan; Lung - drug effects; Lung - pathology; Male; Medical records; Medical research; Medical treatment; Medicine, Experimental; Middle Aged; Mortality; Patient outcomes; Pneumonia; Predictive Value of Tests; Respiratory distress syndrome; Respiratory Tract Infections - pathology; Retrospective Studies; Risk Factors; Rodents; Studies; Thromboembolism; Tomography, X-Ray Computed; Japan

Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) is associated with high mortality. However, few studies have so far reviewed analyses of autopsy findings in patients with AE-IPF. We retrospectively reviewed 52 consecutive patients with AE-IPF who underwent autopsies at five university h...