In Vitro and In Vivo Toxicity Studies on Cymbopogon giganteus Chiov. Leaves Essential Oil from Benin

• Published in: Journal of toxicology Vol. 2020; no. 2020; pp. 1 - 12
• Main Authors: Gbaguidi, Fernand, Lison, Dominique, Lalèyè, Anatole, Mertens, Birgit, Yakoub, Yousof, Uwambayinema, Francine, Toukourou, Habib, Quetin-Leclercq, Joëlle
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 2020; Hindawi; John Wiley & Sons, Inc; Wiley
• Subjects: Acute toxicity; Alveoli; Ames test; Biocompatibility; Body weight; Cymbopogon giganteus; Cytotoxicity; Emulsions; Essential oils; Ethylenediaminetetraacetic acid; Females; Herbal medicine; Histopathology; In vivo methods and tests; Inhalation; Laboratory animals; Leaves; Lecithin; Lungs; Medicinal plants; Medicine, Botanic; Medicine, Herbal; Metabolism; Mortality; Mutation; Oils & fats; Organ weight; Respiration; Salmonella; Salmonella Typhimurium; Solvents; Subacute toxicity; Toxicity; Belgium; Benin; United States > US; Germany

Cymbopogon giganteus Chiov. (Poaceae) is a medicinal plant used to treat various diseases in traditional medicine in several African countries. The present study aims to evaluate the oral and inhalation toxicity as well as the mutagenic effects of the essential oil of Cymbopogon giganteus leaves (EO...