Genetic Framework of Cyclin-Dependent Kinase Function in Arabidopsis

• Published in: Developmental cell Vol. 22; no. 5; pp. 1030 - 1040
• Main Authors: Nowack, Moritz K., Harashima, Hirofumi, Dissmeyer, Nico, Zhao, Xin'Ai, Bouyer, Daniel, Weimer, Annika K., De Winter, Freya, Yang, Fang, Schnittger, Arp
• Format: Journal Article
• Language: English
• Published: Cambridge, MA Elsevier Inc 15.05.2012; Cell Press; Elsevier
• Subjects: Arabidopsis; Arabidopsis - embryology; Arabidopsis - genetics; Arabidopsis - metabolism; Arabidopsis Proteins - genetics; Arabidopsis Proteins - metabolism; Biochemistry, Molecular Biology; Biological and medical sciences; Cdc2 protein; CDC2-CDC28 Kinases - genetics; CDC2-CDC28 Kinases - metabolism; Cell differentiation, maturation, development, hematopoiesis; Cell physiology; Cellular Biology; Cyclin-dependent kinase; Cyclin-Dependent Kinases - genetics; Cyclin-Dependent Kinases - metabolism; Data processing; Development Biology; Differentiation; eukaryotic cells; Evolution; Evolution, Molecular; Flowering; Fundamental and applied biological sciences. Psychology; Genetics; germ cells; interphase; Life Sciences; mammals; Microscopy, Electron, Scanning; Mitosis - physiology; Molecular and cellular biology; Molecular biology; mutants; Mutation; Plant Roots - embryology; Plant Roots - genetics; Plant Roots - metabolism; Plant Shoots - embryology; Plant Shoots - genetics; Plant Shoots - metabolism; Plants genetics; Reproductive Biology; retinoblastoma; S phase; S Phase - physiology; Sexual reproduction; Stem cells; Vegetal Biology; yeasts; Arabidopsis thaliana; Cruciferae; Enzyme; Dicotyledones; Transferases; Angiospermae; Development; Genetics; Spermatophyta; Cyclin dependent kinase

Cyclin-dependent kinases (CDKs) are at the heart of eukaryotic cell-cycle control. The yeast Cdc2/CDC28 PSTAIRE kinase and its orthologs such as the mammalian Cdk1 have been found to be indispensable for cell-cycle progression in all eukaryotes investigated so far. CDKA;1 is the only PSTAIRE kinase...