Generation of neutralizing antibodies against Omicron, Gamma and Delta SARS-CoV-2 variants following CoronaVac vaccination

• Published in: Revista do Instituto de Medicina Tropical de São Paulo Vol. 64; pp. e19 - 6
• Main Authors: Silva Jr, Almir Ribeiro da, Villas-Boas, Lucy Santos, Tozetto-Mendoza, Tania Regina, Honorato, Layla, Paula, Anderson de, Witkin, Steven S., Mendes-Correa, Maria Cassia
• Format: Journal Article
• Language: English
• Published: Brazil Instituto de Medicina Tropical de Sao Paulo 01.01.2022; Instituto de Medicina Tropical de São Paulo; Universidade de São Paulo (USP)
• Subjects: Antibodies; Antibodies, Neutralizing; Antibodies, Viral; Booster; Brazil; CoronaVac vaccine; Coronaviruses; COVID-19 - prevention & control; COVID-19 Vaccines; Delta variant; Gamma variant; Humans; Infections; Life sciences; mRNA vaccines; Mutation; Omicron variant; Original; Pandemics; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; TROPICAL MEDICINE; Vaccination; Brazil; Gamma variant; Omicron variant; Delta variant; CoronaVac vaccine; Booster

Vaccination is a fundamental tool to prevent SARS-CoV-2 infection and to limit the COVID-19 pandemic. The emergence of SARS-CoV-2 variants with multiple mutations has raised serious concerns about the ability of neutralizing antibody responses elicited by prior vaccination to effectively combat thes...