The sedative effects of low-dose medetomidine and butorphanol alone and in combination intravenously in dogs

• Published in: Veterinary anaesthesia and analgesia Vol. 37; no. 1; pp. 1 - 6
• Main Authors: Girard, Nicolas M, Leece, Elizabeth A, Cardwell, JM, Adams, Vicki J, Brearley, Jacqueline C
• Format: Journal Article
• Language: English
• Published: Oxford, UK Elsevier Ltd 01.01.2010; Oxford, UK : Blackwell Publishing Ltd; Blackwell Publishing Ltd
• Subjects: Anesthesia, Intravenous - veterinary; Anesthetics, Combined - administration & dosage; Anesthetics, Combined - pharmacology; Animals; Body Temperature - drug effects; butorphanol; Butorphanol - administration & dosage; Butorphanol - pharmacology; Conscious Sedation - veterinary; dog; Dogs; dosage; dose response; drug evaluation; Female; Heart Rate - drug effects; Hypnotics and Sedatives - administration & dosage; Hypnotics and Sedatives - pharmacology; Infusions, Intravenous - veterinary; intravenous injection; Male; medetomidine; Medetomidine - administration & dosage; Medetomidine - pharmacology; randomized clinical trials; Respiratory Rate - drug effects; sedation; sedatives; Single-Blind Method; butorphanol; medetomidine; dog; sedation

To evaluate the sedative effects of intravenous (IV) medetomidine (1 μg kg−1) and butorphanol (0.1 mg kg−1) alone and in combination in dogs. Prospective, blinded, randomized clinical trial. Sixty healthy (American Society of Anesthesiologists I) dogs, aged 6.2 ± 3.2 years and body mass 26 ± 12.5 kg...