Serotonin system genes contribute to the susceptibility to obesity in Black adolescents

• Published in: Obesity science & practice Vol. 7; no. 4; pp. 441 - 449
• Main Authors: Meng, Ying, Groth, Susan W., Hodgkinson, Colin A., Mariani, Thomas J.
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.08.2021; John Wiley and Sons Inc; Wiley
• Subjects: Adolescents; African Americans; African–American; Alcohol use; Animal models; Body mass index; Body weight; brain; childhood obesity; Drug use; Eating behavior; Energy balance; equations; Families & family life; Genes; Homeostasis; Males; Maternal & child health; Normal distribution; Obesity; Original; Overweight; Population; Serotonin; Single-nucleotide polymorphism; Sociodemographics; Teenagers; waist; Weight control; serotonin; adolescents; African–American; childhood obesity

Objective The importance of the central and peripheral serotonin systems in regulating energy balance and obesity development has been highlighted in animal models. Yet, the role of both serotonin systems has not been systematically assessed in humans. The purpose of this study was to investigate th...