Nucleofection induces transient eIF2α phosphorylation by GCN2 and PERK - Anderson, B R; Karikó, K; Weissman, D (Gene therapy, 2013)
Keywords: 631/154/51/391; 631/1647/2300; 631/250/516; Animals; Biomedical and Life Sciences; Biomedicine; Biotechnology; Cell Biology; Cell Line; Deoxyribonucleic acid; DNA; DNA binding proteins; Drug development; eIF-2 kinase; eIF-2 Kinase - genetics; eIF-2 Kinase - metabolism; Endoplasmic reticulum; Eukaryotic Initiation Factor-2 - genetics; Eukaryotic Initiation Factor-2 - metabolism; Gene Expression; Gene Therapy; Human Genetics; Humans; Initiation factor eIF-2; Initiation factor eIF-2α; Kinases; Mammalian cells; Messenger RNA; Mice; mRNA; Nanotechnology; nucleic acids; original-article; Phosphorylation; Physiological aspects; Protein kinase; Protein Serine-Threonine Kinases - genetics; Protein Serine-Threonine Kinases - metabolism; siRNA; Transfection; Transfection - methods; Translation; United States; eIF2α; GCN2; mRNA therapy; PERK; nucleofection