Non-ulcer Dyspepsia and Duodenal Eosinophilia: An Adult Endoscopic Population-Based Case-Control Study

• Published in: Clinical gastroenterology and hepatology Vol. 5; no. 10; pp. 1175 - 1183
• Main Authors: Talley, Nicholas J, Walker, Marjorie M, Aro, Pertti, Ronkainen, Jukka, Storskrubb, Tom, Hindley, Laura A, Harmsen, W. Scott, Zinsmeister, Alan R, Agréus, Lars
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.10.2007
• Subjects: Adult; Aged; Aged, 80 and over; Biopsy; Diagnosis, Differential; Duodenal Ulcer - diagnosis; Duodenitis - epidemiology; Duodenitis - pathology; Dyspepsia - epidemiology; Dyspepsia - pathology; Endoscopy, Gastrointestinal - methods; Eosinophilia - epidemiology; Eosinophilia - pathology; Eosinophils - pathology; Female; Gastroenterology and Hepatology; Humans; Incidence; Male; Medicin och hälsovetenskap; Middle Aged; Population Surveillance; Retrospective Studies; Severity of Illness Index; Sweden - epidemiology; Sweden; hematoxylin and eosin; major basic protein; OR; CI; H&E; second portion of duodenum; confidence interval; MBP; odds ratio; D1; duodenal bulb; D2

Background & Aims: Functional abnormalities of the duodenum have been observed in non-ulcer dyspepsia. We aimed to identify whether eosinophils in the upper gastrointestinal tract are a biomarker for non-ulcer dyspepsia. Methods: A random sample of an adult Swedish population (n = 1001; mean age...