Highly homologous simian T-cell leukemia virus type 1 genome in Japanese macaques: a large cohort study

• Published in: Virology journal Vol. 21; no. 1; p. 166
• Main Authors: Hiraga, Kou, Kitamura, Tomoya, Kuramitsu, Madoka, Murata, Megumi, Tezuka, Kenta, Okuma, Kazu, Hamaguchi, Isao, Akari, Hirofumi, Mizukami, Takuo
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 30.07.2024; BioMed Central; BMC
• Subjects: adults; Analysis; Animals; Antiviral agents; Apobec3G; Cohort Studies; Control; Deltaretrovirus Infections - epidemiology; Deltaretrovirus Infections - veterinary; Deltaretrovirus Infections - virology; DNA sequencing; Dosage and administration; Epidemiology; etiological agents; Genetic Variation; genome; Genome sequencing; Genome, Viral; HTLV-1; Humans; Identification and classification; Japan; Japanese macaques; leukemia; Macaca fuscata; Macaca fuscata - genetics; Molecular Epidemiology; Nucleotide sequencing; Phylogeny; Primate T-lymphotropic virus 1; RNA viruses; Sequence Analysis, DNA; Simian T-lymphotropic virus 1 - genetics; Simian T-lymphotropic virus 1 - isolation & purification; STLV-1; T-lymphocytes; viruses; Japan; Apobec3G; HTLV-1; STLV-1; Phylogeny; Genome sequencing; Japanese macaques

Simian T-cell leukemia virus type 1 (STLV-1) is a retrovirus closely related to human T-cell leukemia virus type 1 (HTLV-1), the causative agent of adult T-cell leukemia (ATL). It has been shown that Japanese macaques (Macaca fuscata, JMs) are one of the main hosts of STLV-1 and that a high percenta...