A DNA-of-things storage architecture to create materials with embedded memory

• Published in: Nature biotechnology Vol. 38; no. 1; pp. 39 - 43
• Main Authors: Koch, Julian, Gantenbein, Silvan, Masania, Kunal, Stark, Wendelin J., Erlich, Yaniv, Grass, Robert N.
• Format: Journal Article
• Language: English
• Published: New York Nature Publishing Group US 01.01.2020; Nature Publishing Group
• Subjects: 631/1647; 631/1647/48; 631/208/212; 631/61/338; 639/301; Agriculture; Bioinformatics; Biomedical and Life Sciences; Biomedical Engineering/Biotechnology; Biomedicine; Biotechnology; Computer architecture; Data storage; Deoxyribonucleic acid; DNA; DNA - metabolism; DNA biosynthesis; DNA sequencing; DNA synthesis; Electronic devices; Electronic health records; Electronic medical records; Embedding; Gene Library; Information storage and retrieval; Letter; Life Sciences; Methods; Preservation, Biological; Printing, Three-Dimensional; Replication; Silica; Silicon dioxide; Steganography; Surgical implants; Synthesis; Switzerland

DNA storage offers substantial information density 1 – 7 and exceptional half-life 3 . We devised a ‘DNA-of-things’ (DoT) storage architecture to produce materials with immutable memory. In a DoT framework, DNA molecules record the data, and these molecules are then encapsulated in nanometer silica...