Seasonal COVID-19 surge related hospital volumes and case fatality rates
Seasonal and regional surges in COVID-19 have imposed substantial strain on healthcare systems. Whereas sharp inclines in hospital volume were accompanied by overt increases in case fatality rates during the very early phases of the pandemic, the relative impact during later phases of the pandemic a...
Saved in:
Published in | BMC infectious diseases Vol. 22; no. 1; p. 178 |
---|---|
Main Authors | , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
England
BioMed Central Ltd
23.02.2022
BioMed Central BMC |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Seasonal and regional surges in COVID-19 have imposed substantial strain on healthcare systems. Whereas sharp inclines in hospital volume were accompanied by overt increases in case fatality rates during the very early phases of the pandemic, the relative impact during later phases of the pandemic are less clear. We sought to characterize how the 2020 winter surge in COVID-19 volumes impacted case fatality in an adequately-resourced health system.
We performed a retrospective cohort study of all adult diagnosed with COVID-19 in a large academic healthcare system between August 25, 2020 to May 8, 2021, using multivariable logistic regression to examine case fatality rates across 3 sequential time periods around the 2020 winter surge: pre-surge, surge, and post-surge. Subgroup analyses of patients admitted to the hospital and those receiving ICU-level care were also performed. Additionally, we used multivariable logistic regression to examine risk factors for mortality during the surge period.
We studied 7388 patients (aged 52.8 ± 19.6 years, 48% male) who received outpatient or inpatient care for COVID-19 during the study period. Patients treated during surge (N = 6372) compared to the pre-surge (N = 536) period had 2.64 greater odds (95% CI 1.46-5.27) of mortality after adjusting for sociodemographic and clinical factors. Adjusted mortality risk returned to pre-surge levels during the post-surge period. Notably, first-encounter patient-level measures of illness severity appeared higher during surge compared to non-surge periods.
We observed excess mortality risk during a recent winter COVID-19 surge that was not explained by conventional risk factors or easily measurable variables, although recovered rapidly in the setting of targeted facility resources. These findings point to how complex interrelations of population- and patient-level pandemic factors can profoundly augment health system strain and drive dynamic, if short-lived, changes in outcomes. |
---|---|
AbstractList | Abstract Background Seasonal and regional surges in COVID-19 have imposed substantial strain on healthcare systems. Whereas sharp inclines in hospital volume were accompanied by overt increases in case fatality rates during the very early phases of the pandemic, the relative impact during later phases of the pandemic are less clear. We sought to characterize how the 2020 winter surge in COVID-19 volumes impacted case fatality in an adequately-resourced health system. Methods We performed a retrospective cohort study of all adult diagnosed with COVID-19 in a large academic healthcare system between August 25, 2020 to May 8, 2021, using multivariable logistic regression to examine case fatality rates across 3 sequential time periods around the 2020 winter surge: pre-surge, surge, and post-surge. Subgroup analyses of patients admitted to the hospital and those receiving ICU-level care were also performed. Additionally, we used multivariable logistic regression to examine risk factors for mortality during the surge period. Results We studied 7388 patients (aged 52.8 ± 19.6 years, 48% male) who received outpatient or inpatient care for COVID-19 during the study period. Patients treated during surge (N = 6372) compared to the pre-surge (N = 536) period had 2.64 greater odds (95% CI 1.46–5.27) of mortality after adjusting for sociodemographic and clinical factors. Adjusted mortality risk returned to pre-surge levels during the post-surge period. Notably, first-encounter patient-level measures of illness severity appeared higher during surge compared to non-surge periods. Conclusions We observed excess mortality risk during a recent winter COVID-19 surge that was not explained by conventional risk factors or easily measurable variables, although recovered rapidly in the setting of targeted facility resources. These findings point to how complex interrelations of population- and patient-level pandemic factors can profoundly augment health system strain and drive dynamic, if short-lived, changes in outcomes. Seasonal and regional surges in COVID-19 have imposed substantial strain on healthcare systems. Whereas sharp inclines in hospital volume were accompanied by overt increases in case fatality rates during the very early phases of the pandemic, the relative impact during later phases of the pandemic are less clear. We sought to characterize how the 2020 winter surge in COVID-19 volumes impacted case fatality in an adequately-resourced health system. We performed a retrospective cohort study of all adult diagnosed with COVID-19 in a large academic healthcare system between August 25, 2020 to May 8, 2021, using multivariable logistic regression to examine case fatality rates across 3 sequential time periods around the 2020 winter surge: pre-surge, surge, and post-surge. Subgroup analyses of patients admitted to the hospital and those receiving ICU-level care were also performed. Additionally, we used multivariable logistic regression to examine risk factors for mortality during the surge period. We studied 7388 patients (aged 52.8 [+ or -] 19.6 years, 48% male) who received outpatient or inpatient care for COVID-19 during the study period. Patients treated during surge (N = 6372) compared to the pre-surge (N = 536) period had 2.64 greater odds (95% CI 1.46-5.27) of mortality after adjusting for sociodemographic and clinical factors. Adjusted mortality risk returned to pre-surge levels during the post-surge period. Notably, first-encounter patient-level measures of illness severity appeared higher during surge compared to non-surge periods. We observed excess mortality risk during a recent winter COVID-19 surge that was not explained by conventional risk factors or easily measurable variables, although recovered rapidly in the setting of targeted facility resources. These findings point to how complex interrelations of population- and patient-level pandemic factors can profoundly augment health system strain and drive dynamic, if short-lived, changes in outcomes. BACKGROUNDSeasonal and regional surges in COVID-19 have imposed substantial strain on healthcare systems. Whereas sharp inclines in hospital volume were accompanied by overt increases in case fatality rates during the very early phases of the pandemic, the relative impact during later phases of the pandemic are less clear. We sought to characterize how the 2020 winter surge in COVID-19 volumes impacted case fatality in an adequately-resourced health system. METHODSWe performed a retrospective cohort study of all adult diagnosed with COVID-19 in a large academic healthcare system between August 25, 2020 to May 8, 2021, using multivariable logistic regression to examine case fatality rates across 3 sequential time periods around the 2020 winter surge: pre-surge, surge, and post-surge. Subgroup analyses of patients admitted to the hospital and those receiving ICU-level care were also performed. Additionally, we used multivariable logistic regression to examine risk factors for mortality during the surge period. RESULTSWe studied 7388 patients (aged 52.8 ± 19.6 years, 48% male) who received outpatient or inpatient care for COVID-19 during the study period. Patients treated during surge (N = 6372) compared to the pre-surge (N = 536) period had 2.64 greater odds (95% CI 1.46-5.27) of mortality after adjusting for sociodemographic and clinical factors. Adjusted mortality risk returned to pre-surge levels during the post-surge period. Notably, first-encounter patient-level measures of illness severity appeared higher during surge compared to non-surge periods. CONCLUSIONSWe observed excess mortality risk during a recent winter COVID-19 surge that was not explained by conventional risk factors or easily measurable variables, although recovered rapidly in the setting of targeted facility resources. These findings point to how complex interrelations of population- and patient-level pandemic factors can profoundly augment health system strain and drive dynamic, if short-lived, changes in outcomes. Background Seasonal and regional surges in COVID-19 have imposed substantial strain on healthcare systems. Whereas sharp inclines in hospital volume were accompanied by overt increases in case fatality rates during the very early phases of the pandemic, the relative impact during later phases of the pandemic are less clear. We sought to characterize how the 2020 winter surge in COVID-19 volumes impacted case fatality in an adequately-resourced health system. Methods We performed a retrospective cohort study of all adult diagnosed with COVID-19 in a large academic healthcare system between August 25, 2020 to May 8, 2021, using multivariable logistic regression to examine case fatality rates across 3 sequential time periods around the 2020 winter surge: pre-surge, surge, and post-surge. Subgroup analyses of patients admitted to the hospital and those receiving ICU-level care were also performed. Additionally, we used multivariable logistic regression to examine risk factors for mortality during the surge period. Results We studied 7388 patients (aged 52.8 [+ or -] 19.6 years, 48% male) who received outpatient or inpatient care for COVID-19 during the study period. Patients treated during surge (N = 6372) compared to the pre-surge (N = 536) period had 2.64 greater odds (95% CI 1.46-5.27) of mortality after adjusting for sociodemographic and clinical factors. Adjusted mortality risk returned to pre-surge levels during the post-surge period. Notably, first-encounter patient-level measures of illness severity appeared higher during surge compared to non-surge periods. Conclusions We observed excess mortality risk during a recent winter COVID-19 surge that was not explained by conventional risk factors or easily measurable variables, although recovered rapidly in the setting of targeted facility resources. These findings point to how complex interrelations of population- and patient-level pandemic factors can profoundly augment health system strain and drive dynamic, if short-lived, changes in outcomes. Keywords: COVID-19, Surge, Case fatality Seasonal and regional surges in COVID-19 have imposed substantial strain on healthcare systems. Whereas sharp inclines in hospital volume were accompanied by overt increases in case fatality rates during the very early phases of the pandemic, the relative impact during later phases of the pandemic are less clear. We sought to characterize how the 2020 winter surge in COVID-19 volumes impacted case fatality in an adequately-resourced health system. We performed a retrospective cohort study of all adult diagnosed with COVID-19 in a large academic healthcare system between August 25, 2020 to May 8, 2021, using multivariable logistic regression to examine case fatality rates across 3 sequential time periods around the 2020 winter surge: pre-surge, surge, and post-surge. Subgroup analyses of patients admitted to the hospital and those receiving ICU-level care were also performed. Additionally, we used multivariable logistic regression to examine risk factors for mortality during the surge period. We studied 7388 patients (aged 52.8 ± 19.6 years, 48% male) who received outpatient or inpatient care for COVID-19 during the study period. Patients treated during surge (N = 6372) compared to the pre-surge (N = 536) period had 2.64 greater odds (95% CI 1.46-5.27) of mortality after adjusting for sociodemographic and clinical factors. Adjusted mortality risk returned to pre-surge levels during the post-surge period. Notably, first-encounter patient-level measures of illness severity appeared higher during surge compared to non-surge periods. We observed excess mortality risk during a recent winter COVID-19 surge that was not explained by conventional risk factors or easily measurable variables, although recovered rapidly in the setting of targeted facility resources. These findings point to how complex interrelations of population- and patient-level pandemic factors can profoundly augment health system strain and drive dynamic, if short-lived, changes in outcomes. |
ArticleNumber | 178 |
Audience | Academic |
Author | Davis, Tod Coleman, Bernice Ebinger, Joseph E Park, Eunice Roberts, Pamela Cheng, Susan Driver, Matthew Lan, Roy Minissian, Margo B Sun, Nancy Riggs, Richard Botting, Patrick |
Author_xml | – sequence: 1 givenname: Joseph E orcidid: 0000-0002-0587-1572 surname: Ebinger fullname: Ebinger, Joseph E email: joseph.ebinger@csmc.edu, joseph.ebinger@csmc.edu organization: Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA. joseph.ebinger@csmc.edu – sequence: 2 givenname: Roy surname: Lan fullname: Lan, Roy organization: College of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA – sequence: 3 givenname: Matthew surname: Driver fullname: Driver, Matthew organization: Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA – sequence: 4 givenname: Nancy surname: Sun fullname: Sun, Nancy organization: Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA – sequence: 5 givenname: Patrick surname: Botting fullname: Botting, Patrick organization: Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA – sequence: 6 givenname: Eunice surname: Park fullname: Park, Eunice organization: Enterprise Data Intelligence, Cedars-Sinai Medical Center, Los Angeles, California, USA – sequence: 7 givenname: Tod surname: Davis fullname: Davis, Tod organization: Enterprise Data Intelligence, Cedars-Sinai Medical Center, Los Angeles, California, USA – sequence: 8 givenname: Margo B surname: Minissian fullname: Minissian, Margo B organization: Brawerman Nursing Institute and Nursing Research Department, Cedars-Sinai Medical Center, Los Angeles, CA, USA – sequence: 9 givenname: Bernice surname: Coleman fullname: Coleman, Bernice organization: Brawerman Nursing Institute and Nursing Research Department, Cedars-Sinai Medical Center, Los Angeles, CA, USA – sequence: 10 givenname: Richard surname: Riggs fullname: Riggs, Richard organization: Department of Medical Affairs, Cedars-Sinai Medical Center, Los Angeles, CA, USA – sequence: 11 givenname: Pamela surname: Roberts fullname: Roberts, Pamela organization: Department of Biomedical Sciences, Division of Informatics, Cedars-Sinai Medical Center, Los Angeles, CA, USA – sequence: 12 givenname: Susan surname: Cheng fullname: Cheng, Susan organization: Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/35197000$$D View this record in MEDLINE/PubMed |
BookMark | eNqNkktr3DAUhU1JaR7tH-iiGLpJF071Gj02hTB9ZCAw0LTZClm6chxsayrZofn31cRpiKGLooXEvd85XK7OcXEwhAGK4i1GZxhL_jFhIoWqECEVEpiqirwojjATuCKUsoNn78PiOKVbhLCQRL0qDukKK4EQOioursCkMJiuXG-vN58rrMo0xQbKCJ0ZwZU3Ie3aMffvQjf1kEozuNKaBKU3udyO92XMYHpdvPSmS_Dm8T4pfn798mN9UV1uv23W55eV5YiO1YoiRBB2jjCEuVWMKuW8E9I7iblkNeaMUIcVqiXLCm-hFgoE8lY4W2N6UmxmXxfMrd7FtjfxXgfT6odCiI02cWxtB5p75jwgjleEMXDMZFfquXVWSi_qVfb6NHvtproHZ2EYo-kWpsvO0N7oJtxpKXkebj_M6aNBDL8mSKPu22Sh68wAYUqacEokUoLzjL6f0cbk0drBh-xo97g-50oxQZRQmTr7B5WPg761-ft9m-sLwYeFIDMj_B4bM6WkN1ff_5_dXi9ZMrM2hpQi-KetYKT36dNz-nROn35InyZZ9O75Pp8kf-NG_wBsONND |
CitedBy_id | crossref_primary_10_1371_journal_pone_0268853 crossref_primary_10_1016_j_clineuro_2023_107982 crossref_primary_10_1001_jamanetworkopen_2024_13127 crossref_primary_10_1128_mbio_01508_23 crossref_primary_10_1097_CCM_0000000000006263 crossref_primary_10_1002_pds_5580 crossref_primary_10_1075_term_00070_don crossref_primary_10_1186_s12939_023_02037_8 |
Cites_doi | 10.1007/s11469-021-00575-2 10.1001/jama.2020.7310 10.1056/NEJMoa2007764 10.1038/d41586-020-03132-4 10.1016/j.ajem.2020.10.081 10.1371/journal.pmed.1003402 10.1513/AnnalsATS.201804-241OC 10.1007/s11606-016-3936-3 10.1080/20009666.2021.1918440 10.1007/s11606-020-06084-7 10.1016/j.ajic.2020.08.029 10.1146/annurev-virology-012420-022445 10.12788/jhm.3539 10.1016/j.ajic.2021.03.015 10.1377/hlthaff.2020.00904 10.1097/MLR.0b013e31819432e5 10.1001/jamainternmed.2020.8193 10.7326/M21-1213 10.1001/jamanetworkopen.2021.8828 10.12788/jhm.3612 10.1001/jamainternmed.2020.3596 10.2196/24502 10.1097/CCM.0000000000004521 10.1001/jama.2020.15301 10.1186/s40001-021-00524-8 10.1001/jamanetworkopen.2020.29058 |
ContentType | Journal Article |
Copyright | 2022. The Author(s). COPYRIGHT 2022 BioMed Central Ltd. The Author(s) 2022 |
Copyright_xml | – notice: 2022. The Author(s). – notice: COPYRIGHT 2022 BioMed Central Ltd. – notice: The Author(s) 2022 |
DBID | CGR CUY CVF ECM EIF NPM AAYXX CITATION IOV ISR 7X8 5PM DOA |
DOI | 10.1186/s12879-022-07139-2 |
DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef Opposing Viewpoints Resource Center Science in Context MEDLINE - Academic PubMed Central (Full Participant titles) DOAJ Directory of Open Access Journals |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef MEDLINE - Academic |
DatabaseTitleList | MEDLINE - Academic MEDLINE |
Database_xml | – sequence: 1 dbid: DOA name: Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Statistics |
EISSN | 1471-2334 |
EndPage | 178 |
ExternalDocumentID | oai_doaj_org_article_6f4dfe0615244ed4a1903f6cdc88f7b5 A699472979 10_1186_s12879_022_07139_2 35197000 |
Genre | Journal Article |
GeographicLocations | United States |
GeographicLocations_xml | – name: United States |
GrantInformation_xml | – fundername: NHLBI NIH HHS grantid: R01 HL131532 – fundername: NIH HHS grantid: K23-HL153888 – fundername: NIH HHS grantid: U54-CA260591 – fundername: NCI NIH HHS grantid: U54 CA260591 – fundername: NHLBI NIH HHS grantid: K23 HL153888 – fundername: ; – fundername: ; grantid: U54-CA260591; K23-HL153888 |
GroupedDBID | --- -A0 0R~ 23N 2WC 3V. 53G 5VS 6J9 6PF 7X7 88E 8C1 8FI 8FJ AAFWJ AAJSJ AAWTL ABDBF ABUWG ACGFO ACGFS ACIHN ACPRK ACRMQ ADBBV ADINQ ADRAZ ADUKV AEAQA AENEX AFKRA AFPKN AFRAH AHBYD AHMBA AHYZX ALIPV ALMA_UNASSIGNED_HOLDINGS AMKLP AMTXH AOIJS BAPOH BAWUL BCNDV BENPR BFQNJ BMC BPHCQ BVXVI C24 C6C CCPQU CGR CS3 CUY CVF DIK DU5 E3Z EAD EAP EAS EBD EBLON EBS ECM EIF EMB EMK EMOBN ESX F5P FYUFA GROUPED_DOAJ GX1 HMCUK HYE IAO IHR INH INR IOV ISR ITC KQ8 M1P M48 M~E NPM O5R O5S OK1 P2P PGMZT PIMPY PQQKQ PROAC PSQYO RBZ RNS ROL RPM RSV SMD SOJ SV3 TR2 TUS UKHRP W2D WOQ WOW XSB AAYXX CITATION AFGXO 7X8 5PM |
ID | FETCH-LOGICAL-c603t-5300201dd24016c94399dfd78fd81684b16423d190b84603fceb79e70fc7dcb13 |
IEDL.DBID | RPM |
ISSN | 1471-2334 |
IngestDate | Tue Oct 22 15:05:23 EDT 2024 Tue Sep 17 21:01:42 EDT 2024 Fri Oct 25 23:54:50 EDT 2024 Tue Nov 19 20:46:13 EST 2024 Tue Nov 12 22:10:22 EST 2024 Thu Aug 01 19:39:11 EDT 2024 Thu Aug 01 20:10:16 EDT 2024 Thu Nov 21 23:31:48 EST 2024 Sat Sep 28 08:18:06 EDT 2024 |
IsDoiOpenAccess | true |
IsOpenAccess | true |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 1 |
Keywords | COVID-19 Case fatality Surge |
Language | English |
License | 2022. The Author(s). Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c603t-5300201dd24016c94399dfd78fd81684b16423d190b84603fceb79e70fc7dcb13 |
Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ORCID | 0000-0002-0587-1572 |
OpenAccessLink | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864601/ |
PMID | 35197000 |
PQID | 2632809766 |
PQPubID | 23479 |
PageCount | 1 |
ParticipantIDs | doaj_primary_oai_doaj_org_article_6f4dfe0615244ed4a1903f6cdc88f7b5 pubmedcentral_primary_oai_pubmedcentral_nih_gov_8864601 proquest_miscellaneous_2632809766 gale_infotracmisc_A699472979 gale_infotracacademiconefile_A699472979 gale_incontextgauss_ISR_A699472979 gale_incontextgauss_IOV_A699472979 crossref_primary_10_1186_s12879_022_07139_2 pubmed_primary_35197000 |
PublicationCentury | 2000 |
PublicationDate | 2022-02-23 |
PublicationDateYYYYMMDD | 2022-02-23 |
PublicationDate_xml | – month: 02 year: 2022 text: 2022-02-23 day: 23 |
PublicationDecade | 2020 |
PublicationPlace | England |
PublicationPlace_xml | – name: England – name: London |
PublicationTitle | BMC infectious diseases |
PublicationTitleAlternate | BMC Infect Dis |
PublicationYear | 2022 |
Publisher | BioMed Central Ltd BioMed Central BMC |
Publisher_xml | – name: BioMed Central Ltd – name: BioMed Central – name: BMC |
References | S Bansal (7139_CR25) 2021; 11 GA Roth (7139_CR23) 2021; 4 C van Walraven (7139_CR12) 2009; 47 H Ledford (7139_CR8) 2020; 587 MT Bassett (7139_CR22) 2020; 17 CO Eriksson (7139_CR2) 2017; 32 GL Anesi (7139_CR1) 2018; 15 S Gupta (7139_CR4) 2020; 180 C Keeley (7139_CR15) 2020; 39 DA Chokshi (7139_CR14) 2020; 323 N Rosenthal (7139_CR20) 2020; 3 S SeyedAlinaghi (7139_CR10) 2021; 26 FS Vahidy (7139_CR24) 2020; 324 JJ Baugh (7139_CR27) 2021; 46 AT Janke (7139_CR7) 2021; 16 DA Asch (7139_CR28) 2021; 181 T Rebmann (7139_CR19) 2021; 49 7139_CR29 7139_CR6 7139_CR30 7139_CR9 BL Block (7139_CR3) 2021; 16 CV Cardemil (7139_CR21) 2021; 7 R Kleinpell (7139_CR13) 2020; 48 JH Beigel (7139_CR17) 2020; 383 7139_CR5 T Rebmann (7139_CR18) 2021; 49 MG Argenziano (7139_CR16) 1996; 2020 M Moriyama (7139_CR11) 2020; 7 Y Sürme (7139_CR26) 2021 |
References_xml | – ident: 7139_CR9 – year: 2021 ident: 7139_CR26 publication-title: Int J Mental Health Addiction doi: 10.1007/s11469-021-00575-2 contributor: fullname: Y Sürme – volume: 2020 start-page: m369 year: 1996 ident: 7139_CR16 publication-title: Bmj contributor: fullname: MG Argenziano – volume: 323 start-page: 1996 issue: 20 year: 2020 ident: 7139_CR14 publication-title: JAMA doi: 10.1001/jama.2020.7310 contributor: fullname: DA Chokshi – volume: 383 start-page: 1813 issue: 19 year: 2020 ident: 7139_CR17 publication-title: N Engl J Med doi: 10.1056/NEJMoa2007764 contributor: fullname: JH Beigel – volume: 587 start-page: 190 issue: 7833 year: 2020 ident: 7139_CR8 publication-title: Nature doi: 10.1038/d41586-020-03132-4 contributor: fullname: H Ledford – volume: 46 start-page: 476 year: 2021 ident: 7139_CR27 publication-title: Am J Emerg Med doi: 10.1016/j.ajem.2020.10.081 contributor: fullname: JJ Baugh – volume: 17 start-page: e1003402 issue: 10 year: 2020 ident: 7139_CR22 publication-title: PLoS Med doi: 10.1371/journal.pmed.1003402 contributor: fullname: MT Bassett – volume: 15 start-page: 1328 issue: 11 year: 2018 ident: 7139_CR1 publication-title: Ann Am Thorac Soc doi: 10.1513/AnnalsATS.201804-241OC contributor: fullname: GL Anesi – volume: 32 start-page: 686 issue: 6 year: 2017 ident: 7139_CR2 publication-title: J Gen Intern Med doi: 10.1007/s11606-016-3936-3 contributor: fullname: CO Eriksson – volume: 11 start-page: 299 issue: 3 year: 2021 ident: 7139_CR25 publication-title: J Commun Hosp Intern Med Perspect doi: 10.1080/20009666.2021.1918440 contributor: fullname: S Bansal – ident: 7139_CR5 doi: 10.1007/s11606-020-06084-7 – volume: 49 start-page: 434 issue: 4 year: 2021 ident: 7139_CR19 publication-title: Am J Infect Control doi: 10.1016/j.ajic.2020.08.029 contributor: fullname: T Rebmann – volume: 7 start-page: 83 issue: 1 year: 2020 ident: 7139_CR11 publication-title: Ann Rev Virol doi: 10.1146/annurev-virology-012420-022445 contributor: fullname: M Moriyama – ident: 7139_CR30 – volume: 16 start-page: 211 issue: 4 year: 2021 ident: 7139_CR7 publication-title: J Hosp Med doi: 10.12788/jhm.3539 contributor: fullname: AT Janke – volume: 49 start-page: 657 issue: 6 year: 2021 ident: 7139_CR18 publication-title: Am J Infect Control doi: 10.1016/j.ajic.2021.03.015 contributor: fullname: T Rebmann – ident: 7139_CR6 – volume: 39 start-page: 1426 issue: 8 year: 2020 ident: 7139_CR15 publication-title: Health Aff (Millwood) doi: 10.1377/hlthaff.2020.00904 contributor: fullname: C Keeley – volume: 47 start-page: 626 issue: 6 year: 2009 ident: 7139_CR12 publication-title: Med Care doi: 10.1097/MLR.0b013e31819432e5 contributor: fullname: C van Walraven – volume: 181 start-page: 471 issue: 4 year: 2021 ident: 7139_CR28 publication-title: JAMA Intern Med doi: 10.1001/jamainternmed.2020.8193 contributor: fullname: DA Asch – ident: 7139_CR29 doi: 10.7326/M21-1213 – volume: 4 start-page: e218828 issue: 5 year: 2021 ident: 7139_CR23 publication-title: JAMA Netw Open doi: 10.1001/jamanetworkopen.2021.8828 contributor: fullname: GA Roth – volume: 16 start-page: 215 issue: 4 year: 2021 ident: 7139_CR3 publication-title: J Hosp Med doi: 10.12788/jhm.3612 contributor: fullname: BL Block – volume: 180 start-page: 1436 issue: 11 year: 2020 ident: 7139_CR4 publication-title: JAMA Intern Med doi: 10.1001/jamainternmed.2020.3596 contributor: fullname: S Gupta – volume: 7 start-page: e24502 issue: 1 year: 2021 ident: 7139_CR21 publication-title: JMIR Public Health Surveill doi: 10.2196/24502 contributor: fullname: CV Cardemil – volume: 48 start-page: e846 issue: 10 year: 2020 ident: 7139_CR13 publication-title: Crit Care Med doi: 10.1097/CCM.0000000000004521 contributor: fullname: R Kleinpell – volume: 324 start-page: 998 issue: 10 year: 2020 ident: 7139_CR24 publication-title: JAMA doi: 10.1001/jama.2020.15301 contributor: fullname: FS Vahidy – volume: 26 start-page: 51 issue: 1 year: 2021 ident: 7139_CR10 publication-title: Eur J Med Res doi: 10.1186/s40001-021-00524-8 contributor: fullname: S SeyedAlinaghi – volume: 3 start-page: e2029058 issue: 12 year: 2020 ident: 7139_CR20 publication-title: JAMA Netw Open doi: 10.1001/jamanetworkopen.2020.29058 contributor: fullname: N Rosenthal |
SSID | ssj0017829 |
Score | 2.4283507 |
Snippet | Seasonal and regional surges in COVID-19 have imposed substantial strain on healthcare systems. Whereas sharp inclines in hospital volume were accompanied by... Background Seasonal and regional surges in COVID-19 have imposed substantial strain on healthcare systems. Whereas sharp inclines in hospital volume were... BACKGROUNDSeasonal and regional surges in COVID-19 have imposed substantial strain on healthcare systems. Whereas sharp inclines in hospital volume were... Abstract Background Seasonal and regional surges in COVID-19 have imposed substantial strain on healthcare systems. Whereas sharp inclines in hospital volume... |
SourceID | doaj pubmedcentral proquest gale crossref pubmed |
SourceType | Open Website Open Access Repository Aggregation Database Index Database |
StartPage | 178 |
SubjectTerms | Adult Aged Case fatality COVID-19 Epidemics Female Hospital Mortality Hospital utilization Hospitals Humans Male Middle Aged Retrospective Studies SARS-CoV-2 Seasons Social aspects Statistics Surge United States |
SummonAdditionalLinks | – databaseName: DOAJ Directory of Open Access Journals dbid: DOA link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1LTxRBEO4YDsYLUREdRdIaEw6kwzz7cQSELCZIwivcOv0EL7PG2f3_VvXMku0Qw8XjTNdh5qvq_qpm6kHIN1WWDmihYcLhpxvjLAO74ayJYBxK2c4prEY-_8lnN-2Pu-5ubdQX5oSN7YFH4A54bH0MSLxARMG3Bhisidx5J2UUduxeWtarYGr6fwC8p1YlMpIfDHAKC8Uwcx2jMsXqjIZSt_6nZ_IaKeUJk2sMdPqabE6uIz0cH_kNeRH6t-Tl-fRzfIvMroJJjjU9vrg9-84qRQcseqapXiV4-jDNCKHjkTRQ03vqgMZoxI844I9TbBwxvCM3pyfXxzM2DUpgjpfNgnUNen2V90DPFXcKYwwfvZDR41iN1kJMVDcekLPgbgB8LlihgiijE97ZqtkmG_28Dx8IrUyMlQlCdQ6A76QRjoPCuI0-4FVB9le46d9jPwyd4gjJ9YiyBpR1QlnXBTlCaB8lsZd1ugEa1pOG9XMaLshXVIzGbhU9psPcm-Uw6LOLW33IlWohPBDqX0JXl5nQ3iQU56BHZ6YSBHh17IKVSe5kkrDnXLb8ZWUkGpcwUa0P8-Wgsf29LMHH4wV5PxrN49vjLEQBFFQQkZlTBk--0v96SC2_peSguOrj_8DzE3lVp51Qs7rZIRuLP8vwGTyrhd1Nm-gvP4weuw priority: 102 providerName: Directory of Open Access Journals – databaseName: Scholars Portal Journals: Open Access dbid: M48 link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV3da9RAEF9KBfFFtH5Fa1lF8EFWk2yyHw8ibbVchbNgvdK3ZbMfbUFyerkD_e-d2eTaBuuDj3c75C6zM_v7TTIfhLzSee4AFjiTDh_dWNcwsBvBeATj0LqpncZq5OkXMZlVn0_r0w2yHnc0KLC7MbTDeVKzxfe3v37-_gAO_z45vBLvOjhjpWaYl44xl2ZwJN8qARkxxWtaXb1VADTUqdpIFqzkvFoX0dx4jRFQpX7-f5_a12BrnFJ5DaMO7pG7A7mku7013Ccbod0it6fD6_MHZHIcbKLedP_o5PAjKzTtsCyapoqW4On5MEWE9odWR23rqQOgoxEf8wBjp9haontIZgefvu1P2DBKgTmR8yWrOfLCwnsA8EI4jVGIj16q6HHwRtVA1FRyD-ygAUKS8-hCI3WQeXTSu6bgj8hmO2_DE0ILG2Nhg9S1i5WvlZVOwJaKJvqAnzLyZq0386PvmGFSpKGE6bVsQMsmadmUGdlD1V5KYrfr9MV8cWYG5zECfigGJF9ARoKvLPxPHoXzTqkomzojL3FjDPazaDFh5syuus4cHp2YXaF1BQGE1P8SOv46Eno9CMU57KOzQ5EC3Dr2yRpJbo8kwSvdaPnF2kgMLmEqWxvmq85gg3yVAwsUGXncG83l3eO0RAkglRE5MqeResYr7cV5agqulICNK57-l_afkTtlMvkS_GGbbC4Xq_AcSNay2Ume8weffx6X priority: 102 providerName: Scholars Portal |
Title | Seasonal COVID-19 surge related hospital volumes and case fatality rates |
URI | https://www.ncbi.nlm.nih.gov/pubmed/35197000 https://search.proquest.com/docview/2632809766 https://pubmed.ncbi.nlm.nih.gov/PMC8864601 https://doaj.org/article/6f4dfe0615244ed4a1903f6cdc88f7b5 |
Volume | 22 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1La9tAEF6SFEovpe8oSc22FHooivXcxzF2E5yCk-A0wfSyaF9JoJFDZP__zqylYFF66WVB3hGWZmd2vlnNg5AvMkkMmIU85gaPbiqjY5AbFucehENKXRqJ2cjTMza5Kn7My_kWKbtcmBC0b_TdYf37_rC-uw2xlQ_3ZtjFiQ0vpmMhWAGOxHCbbIP57Vz09tMBmDzZZccINmxgA-YyxqB1dMhkjP1rsCsdTzCrbcMYhZr9f-_MG6apHza5YYdOXpGXLYCkR-sHfU22XP2GPJ-2n8jfksmlqwK8puPz69PvcSppg6nPNGStOEtv204hdL0xNbSqLTVgzKjHoxxA5RTLRzTvyNXJ8c_xJG7bJcSGJfkyLnPEfqm1YKRTZiR6GtZbLrzF5hqFBs8oyy0gAA2gI8m9cZpLxxNvuDU6zd-TnXpRu11C08r7tHJclsYXthQVNwyWjWlvHV5F5FvHN_WwroqhgjchmFozXAHDVWC4yiIyQtY-UWJF6_DD4vFGteuqGPyRdwiwAHA4W1TwnLlnxhohPNdlRD7jwiisWVFjUMxNtWoadXp-rY6YlAU4CVz-i-hy1iP62hL5BayjqdpEBHh1rIXVozzoUYLmmd70p05IFE5huFrtFqtGYRF8kQDSYxH5sBaap7fvZC8ivCdOPfb0Z0APQuHvVu73_vvOffIiC5qQxVl-QHaWjyv3EUDVUg9AleYcRjFOB-TZ6PjsYjYIBxQwTgsB42z0axBU7Q_uXyTY |
link.rule.ids | 230,314,727,780,784,864,885,2102,24318,27924,27925,31720,33267,33745,53791,53793 |
linkProvider | National Library of Medicine |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwELZKkYBLxZuUAgYhcUDuJnFix8eyUO1Ct0X0od6s-NVWotmq2f3_zHiTaiPEhWPiiWKPx55v7HkQ8lGlqQW1wJm0eHRTW8NAbgTjAYRDKVNahdHIs0MxOS2-n5fnG6TsY2Gi0741V7vN7-vd5uoy-lbeXNtR7yc2-jkbV5UowJAY3SP3Sy5V1hvp3eUBKD3Vx8dUYtTCFiwVQ7d1NMkUwwo2WJdOphjXtqaOYtb-v_fmNeU0dJxc00T7j8lWByHp3qqrT8iGb56SB7PukvwZmRz7OgJsOj46m35lmaItBj_TGLfiHb3saoXQ1dbU0rpx1II6owEPcwCXU0wg0T4np_vfTsYT1hVMYFakfMFKjugvcw7UdCasQlvDBSer4LC8RmHANsq5AwxgAHakPFhvpPIyDVY6azL-gmw288a_IjSrQ8hqL1VpQ-HKqpZWwMQJE5zHp4R87vmmb1Z5MXS0JyqhVwzXwHAdGa7zhHxB1t5RYk7r-GJ-e6G7mdUCfhQ8QiyAHN4VNfSTB2GdraogTZmQDzgxGrNWNOgWc1Ev21ZPj870nlCqADNBqn8RHf8aEH3qiMIc5tHWXSgCDB2zYQ0odwaUsPbsoPl9LyQam9BhrfHzZasxDX6VAtYTCXm5Epq70feylxA5EKcBe4YtsBJi6u9O8rf_-8t35OHkZHagD6aHP16TR3lcFTnL-Q7ZXNwu_RuAWAvzNi6oPye3IgE |
linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwELagSBUXxLtpCxiExAGleTix42PZstoFtq0orXqz4ldbiWZXze7_Z8abVBshLhwTTxR7PPZ8Y8-DkI8yTQ2oBRYLg0c3tdExyA2PmQfhkFKXRmI08uyYT86Lb5fl5Uapr-C0b_TNQfP79qC5uQ6-lYtbk_R-YsnpbFRVvABDIllYnzwkj0oGQtYb6t0FAig-2cfIVDxpYRsWMkbXdTTLZIxVbLA2nUgxtm1DJYXM_X_vzxsKaug8uaGNxk_Jkw5G0sN1d5-RB655TrZn3UX5CzI5c3UA2XR0cjE9ijNJWwyApiF2xVl63dULoevtqaV1Y6kBlUY9HugANqeYRKJ9Sc7HX3-NJnFXNCE2PGXLuGSIADNrQVVn3Ei0N6y3ovIWS2wUGuyjnFnAARqgR8q8cVpIJ1JvhDU6Y6_IVjNv3A6hWe19VjshS-MLW1a1MBwmj2tvHT5F5HPPN7VY58ZQwaaouFozXAHDVWC4yiPyBVl7T4l5rcOL-d2V6mZXcfiRdwizAHY4W9TQT-a5saaqvNBlRD7gxCjMXNGga8xVvWpbNT25UIdcygJMBSH_RXT2c0D0qSPyc5hHU3fhCDB0zIg1oNwfUML6M4Pm972QKGxCp7XGzVetwlT4VQp4j0fk9Vpo7kffy15ExECcBuwZtsBqCOm_O-nf_e8v35Ht06Ox-jE9_r5HHudhUeRxzvbJ1vJu5d4Aylrqt2E9_QFRjSMU |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Seasonal+COVID-19+surge+related+hospital+volumes+and+case+fatality+rates&rft.jtitle=BMC+infectious+diseases&rft.au=Ebinger%2C+Joseph+E.&rft.au=Lan%2C+Roy&rft.au=Driver%2C+Matthew&rft.au=Sun%2C+Nancy&rft.date=2022-02-23&rft.issn=1471-2334&rft.eissn=1471-2334&rft.volume=22&rft.issue=1&rft_id=info:doi/10.1186%2Fs12879-022-07139-2&rft.externalDBID=n%2Fa&rft.externalDocID=10_1186_s12879_022_07139_2 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1471-2334&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1471-2334&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1471-2334&client=summon |