Comparative genomics of biotechnologically important yeasts

• Published in: Proceedings of the National Academy of Sciences - PNAS Vol. 113; no. 35; pp. 9882 - 9887
• Main Authors: Riley, Robert, Haridas, Sajeet, Wolfe, Kenneth H., Lopes, Mariana R., Hittinger, Chris Todd, Göker, Markus, Salamov, Asaf A., Wisecaver, Jennifer H., Long, Tanya M., Calvey, Christopher H., Aerts, Andrea L., Barry, Kerrie W., Choi, Cindy, Clum, Alicia, Coughlan, Aisling Y., Deshpande, Shweta, Douglass, Alexander P., Hanson, Sara J., Klenk, Hans-Peter, LaButti, Kurt M., Lapidus, Alla, Lindquist, Erika A., Lipzen, Anna M., Meier-Kolthoff, Jan P., Ohm, Robin A., Otillar, Robert P., Pangilinan, Jasmyn L., Peng, Yi, Rokas, Antonis, Rosa, Carlos A., Scheuner, Carmen, Sibirny, Andriy A., Slot, Jason C., Stielow, J. Benjamin, Sun, Hui, Kurtzman, Cletus P., Blackwell, Meredith, Grigoriev, Igor V., Jeffries, Thomas W.
• Format: Journal Article
• Language: English
• Published: United States National Academy of Sciences 30.08.2016; Proceedings of the National Academy of Sciences
• Subjects: Ascomycetes; Ascomycota - classification; Ascomycota - genetics; Ascomycota - metabolism; BASIC BIOLOGICAL SCIENCES; bioenergy; bioengineering; Biological Sciences; biotechnological yeasts; Biotechnology; Biotechnology - methods; Evolution, Molecular; Fungal Proteins - genetics; Fungal Proteins - metabolism; genetic code; Genetic Code - genetics; Genome, Fungal - genetics; Genomics; Genomics - methods; Heterochromatin; loci; Metabolic Networks and Pathways - genetics; microbiology; multigene family; Pachysolen tannophilus; Phylogenetics; Phylogeny; rhamnose; sequence analysis; Species Specificity; xylose; Yeast; Yeasts; Yeasts - classification; Yeasts - genetics; Yeasts - metabolism; bioenergy; microbiology; genomics; biotechnological yeasts; genetic code

Ascomycete yeasts are metabolically diverse, with great potential for biotechnology. Here, we report the comparative genome analysis of 29 taxonomically and biotechnologically important yeasts, including 16 newly sequenced. We identify a genetic code change, CUG-Ala, in Pachysolen tannophilus in the...