Identification of THY1 as a novel thyrotrope marker and THY1 antibody-mediated thyrotrope isolation in the rat anterior pituitary gland

• Published in: Biochemical and biophysical research communications Vol. 480; no. 2; pp. 273 - 279
• Main Authors: Horiguchi, Kotaro, Nakakura, Takashi, Yoshida, Saishu, Tsukada, Takehiro, Kanno, Naoko, Hasegawa, Rumi, Takigami, Shu, Ohsako, Shunji, Kato, Takako, Kato, Yukio
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 11.11.2016
• Subjects: adults; Animals; anterior pituitary; Anterior pituitary gland; antibodies; Biomarkers - metabolism; CD18 antigen; CD18 Antigens - metabolism; CD90; Cell Separation - methods; Cell surface glycoprotein; immunohistochemistry; in situ hybridization; Integrin-β2; isolation techniques; ligands; Male; messenger RNA; Pituitary Gland, Anterior - cytology; Pituitary Gland, Anterior - immunology; rats; Rats, Wistar; Thy-1 Antigens - genetics; Thy-1 Antigens - metabolism; THY1; thymocytes; Thymocytes - immunology; Thymocytes - metabolism; thyrotropin; Thyrotropin - metabolism; thyrotropin-releasing hormone; TSH; Western blotting; Anterior pituitary gland; TSH; THY1; Integrin-β2; Cell surface glycoprotein; CD90

Contact-dependent (juxtacrine) signaling is important for local cell-to-cell interaction and has received attention in recent years regarding its role in pituitary function, differentiation, and development. This study investigated one of the juxtacrine-related molecules, thymocyte differentiation a...