CT scan findings of probable usual interstitial pneumonitis have a high predictive value for histologic usual interstitial pneumonitis

• Published in: Chest Vol. 147; no. 2; p. 450
• Main Authors: Chung, Jonathan H, Chawla, Ashish, Peljto, Anna L, Cool, Carlyne D, Groshong, Steve D, Talbert, Janet L, McKean, David F, Brown, Kevin K, Fingerlin, Tasha E, Schwarz, Marvin I, Schwartz, David A, Lynch, David A
• Format: Journal Article
• Language: English
• Published: United States 01.02.2015
• Subjects: Aged; Female; Genotype; Humans; Lung Diseases, Interstitial - diagnostic imaging; Lung Diseases, Interstitial - genetics; Lung Diseases, Interstitial - pathology; Male; Middle Aged; Mucin-5B - genetics; Polymorphism, Single Nucleotide; Predictive Value of Tests; Tomography, X-Ray Computed

The current usual interstitial pneumonitis (UIP)/idiopathic pulmonary fibrosis CT scan classification system excludes probable UIP as a diagnostic category. We sought to determine the predictive effect of probable UIP on CT scan on histology and the effect of the promoter polymorphism in MUC5B (rs35...