Serum Vitamin D Concentration and Prostate Cancer Risk: A Nested Case–Control Study

• Published in: JNCI : Journal of the National Cancer Institute Vol. 100; no. 11; pp. 796 - 804
• Main Authors: Ahn, Jiyoung, Peters, Ulrike, Albanes, Demetrius, Purdue, Mark P., Abnet, Christian C., Chatterjee, Nilanjan, Horst, Ronald L., Hollis, Bruce W., Huang, Wen-Yi, Shikany, James M., Hayes, Richard B.
• Format: Journal Article
• Language: English
• Published: Cary, NC Oxford University Press 04.06.2008; Oxford Publishing Limited (England)
• Subjects: Aged; Biological and medical sciences; Case-Control Studies; Clinical Trials as Topic; Humans; Incidence; Logistic Models; Male; Mass Screening - methods; Medical sciences; Middle Aged; Nephrology. Urinary tract diseases; Odds Ratio; Oncology; Prospective Studies; Prostate cancer; Prostatic Neoplasms - blood; Prostatic Neoplasms - chemically induced; Prostatic Neoplasms - epidemiology; Prostatic Neoplasms - pathology; Risk Assessment; Risk Factors; Tumors; Tumors of the urinary system; United States - epidemiology; Urinary tract. Prostate gland; Vitamin D; Vitamin D - adverse effects; Vitamin D - analogs & derivatives; Vitamin D - blood; United States; North America; America; Human; Urinary system disease; Prostate disease; Malignant tumor; Case control study; Epidemiology; Urology; Cancerology; Vitamin D; Risk factor; Serum; Male genital diseases; Prostate cancer; Public health; Cancer

Background Epidemiological studies have yielded inconsistent associations between vitamin D status and prostate cancer risk, and few studies have evaluated whether the associations vary by disease aggressiveness. We investigated the association between vitamin D status, as determined by serum 25-hyd...