Targeting tumor O‐glycosylation modulates cancer–immune‐cell crosstalk and enhances anti‐PD‐1 immunotherapy in head and neck cancer - Lin, Mei‐Chun; Chuang, Ya‐Ting; Wu, Hsin‐Yi; Hsu, Chia‐Lang; Lin, Neng‐Yu; Huang, Min‐Chuan; Lou, Pei‐Jen (Molecular oncology, 2024)
Keywords: Animal models; Animals; Antibodies; Apoptosis; Cancer Immunotherapy; Cell death; Cell Line, Tumor; Cloning; core 1 β1,3‐galactosyltransferase; Cytokines; Cytotoxicity; Drug therapy; Glycosylation; Head & neck cancer; Head and Neck Cancer; Head and Neck Neoplasms - drug therapy; IL‐6; immune checkpoint inhibitor; Immunotherapy; Inflammation; Interleukin 6; Interleukin-6 - metabolism; Interleukins; Itraconazole; Laboratory animals; Ligands; Lymphocytes T; Macrophages; Metastasis; Mice; O‐glycosylation; PD-1 protein; Phenotypes; Plasmids; Polysaccharides - metabolism; Proteasomes; Protein binding; Proteins; Scientific equipment and supplies industry; Secretome; Stromal cells; T cells; Tumor cells; Tumor Microenvironment; Tumors; Viral antibodies; United States; Taiwan; United States--US; O-glycosylation; immune checkpoint inhibitor; itraconazole; head and neck cancer; core 1 β1,3-galactosyltransferase; IL-6