A potent anti‐dengue human antibody preferentially recognizes the conformation of E protein monomers assembled on the virus surface - Fibriansah, Guntur; Tan, Joanne L; Smith, Scott A; de Alwis, Adamberage R; Ng, Thiam‐Seng; Kostyuchenko, Victor A; Ibarra, Kristie D; Wang, Jiaqi; Harris, Eva; de Silva, Aravinda; Crowe, James E; Lok, Shee‐Mei (EMBO molecular medicine, 2014)
Keywords: Amino Acid Sequence; Animals; Antibodies, Monoclonal - immunology; Antibodies, Monoclonal - pharmacology; Antibodies, Monoclonal - therapeutic use; Antibodies, Neutralizing - immunology; Antibodies, Viral - immunology; Bone marrow; Cell Line; cryoEM; Dengue - drug therapy; Dengue - veterinary; Dengue fever; dengue virus; Dengue Virus - metabolism; EMBO19; EMBO23; Encephalitis; Epitopes; Epitopes - chemistry; Epitopes - immunology; Fab; human antibody; Humans; Immunoglobulin Fab Fragments - chemistry; Immunoglobulin Fab Fragments - immunology; Immunoglobulins; Infections; Mice; Microscopy; Molecular Dynamics Simulation; Molecular Sequence Data; Monoclonal antibodies; Monomers; neutralization; Protein structure; Protein Structure, Tertiary; Proteins; Quaternary structure; Research Article; Serotypes; Standard deviation; structure; Tropical diseases; Variance analysis; Viral envelope proteins; Viral Envelope Proteins - chemistry; Viral Envelope Proteins - immunology; Virus Internalization - drug effects; West Nile virus; cryoEM; human antibody; neutralization; structure; dengue virus