Predictors of development of cardiac and digestive disorders among patients with indeterminate chronic Chagas Disease

• Published in: PLoS neglected tropical diseases Vol. 15; no. 8; p. e0009680
• Main Authors: Nunes da Costa, Erika Alessandra Pellison, Victória, Cassiano, Fortaleza, Carlos Magno Castelo Branco
• Format: Journal Article
• Language: English
• Published: San Francisco Public Library of Science 01.08.2021; Public Library of Science (PLoS)
• Subjects: Abnormalities; Asymptomatic; Benznidazole; Biology and Life Sciences; Body mass; Body mass index; Body size; Cardiomyopathy; Chagas disease; Cohorts; Complications and side effects; Confidence intervals; Demography; Digestive system diseases; Disorders; Gender; Heart attacks; Heart diseases; Heart failure; Housing conditions; Impact analysis; Malformations; Medicine and Health Sciences; Patients; People and places; Regression analysis; Regression models; Risk factors; Serology; Statistical analysis; Statistical methods; Therapy; Tropical diseases; Trypanosomiasis; Vector-borne diseases; Brazil
• ISSN: 1935-2735; 1935-2727; 1935-2735
• DOI: 10.1371/journal.pntd.0009680

American trypanosomiasis (Chagas disease, CD) affects circa 7 million persons worldwide. While of those persons present the asymptomatic, indeterminate chronic form (ICF), many will eventually progress to cardiac or digestive disorders. We studied a nonconcurrent (retrospective) cohort of patients a...