Potocytosis: Sequestration and Transport of Small Molecules by Caveolae

• Published in: Science (American Association for the Advancement of Science) Vol. 255; no. 5043; pp. 410 - 411
• Main Authors: Richard G. W. Anderson, Kamen, Barton A., Rothberg, Karen G., Lacey, Stephen W.
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for the Advancement of Science 24.01.1992; American Association for the Advancement of Science; The American Association for the Advancement of Science
• Subjects: Adipocytes; Biological and medical sciences; Biological transport; Carrier Proteins - physiology; Caveolae; Cell Membrane - physiology; Cell Membrane - ultrastructure; Cell membranes; Cell physiology; Cells; Cells, Cultured; Cellular biology; Cholesterols; Cytology; Endocytosis; Folate Receptors, GPI-Anchored; folic acid; Folic Acid - metabolism; Fundamental and applied biological sciences. Psychology; Glycolipids - physiology; Glycosylphosphatidylinositols; In Vitro Techniques; Internalization; Kinetics; Ligands; Membrane and intracellular transports; Membrane Glycoproteins - physiology; Membrane proteins; Molecular and cellular biology; Molecules; Narcotics; Perspectives; Phosphatidylinositols - physiology; potocytosis; Proteins; Receptors; Receptors, Cell Surface - physiology; sequestering; transport; Plasmalemma; Endocytosis; Membrane protein; Membrane transport; Internalization; Folic acid
• ISSN: 0036-8075; 1095-9203
• DOI: 10.1126/science.1310359

The uptake of small molecules by eukaryotic cells is thought to occur by movement across the membrane through water-filled channels, carriers or transporters. Potocytosis, which is the sequestration and transport of small molecules by Caveolae, is described.