Prospective safety surveillance study of ACAM2000 smallpox vaccine in deploying military personnel

• Published in: Vaccine Vol. 38; no. 46; pp. 7323 - 7330
• Main Authors: Faix, Dennis J., Gordon, Daniel M., Perry, Lori N., Raymond-Loher, Ilfra, Tati, Nita, Lin, Grace, DiPietro, Gina, Selmani, Alex, Decker, Michael D.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 27.10.2020; Elsevier Limited
• Subjects: Adjudication; Allergy and Immunology; Biological & chemical terrorism; Cardiovascular adverse event; Clinical trials; cohort studies; Electrocardiography; Enrollments; exercise; gender; Guillain-Barre syndrome; Heart diseases; Humans; Laboratories; Military Personnel; monitoring; Myocarditis; Myopericarditis; Observational studies; odds ratio; Pericarditis; Prospective Studies; regression analysis; Regression models; Risk analysis; risk assessment; Risk factors; Smallpox; Smallpox vaccine; Smallpox Vaccine - adverse effects; Surveillance; Vaccination; Vaccines; Vaccinia; United States > US; Texas; Myocarditis; Cardiovascular adverse event; Pericarditis; Myopericarditis; Vaccinia; Smallpox vaccine

•Smallpox vaccine is provided by CDC and DOD for use in specified circumstances.•The risk of myopericarditis following smallpox vaccine is not well defined.•The odds of myopericarditis after smallpox vaccine was 1.3 (not significant)•Careful screening to exclude those at risk appeared to be a succes...