Inactivated influenza vaccine effectiveness and an analysis of repeated vaccination for children during the 2016/17 season

• Published in: Vaccine Vol. 36; no. 37; pp. 5510 - 5518
• Main Authors: Shinjoh, Masayoshi, Sugaya, Norio, Yamaguchi, Yoshio, Iibuchi, Noriko, Kamimaki, Isamu, Goto, Anna, Kobayashi, Hisato, Kobayashi, Yasuaki, Shibata, Meiwa, Tamaoka, Satoshi, Nakata, Yuji, Narabayashi, Atsushi, Nishida, Mitsuhiro, Hirano, Yasuhiro, Munenaga, Takeshi, Morita, Kumiko, Mitamura, Keiko, Takahashi, Takao
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 05.09.2018; Elsevier Limited
• Subjects: Adolescent; Age; Allergy and Immunology; Case-Control Studies; Child; Child, Preschool; Children; Children & youth; Diagnostic systems; Effectiveness; Enrollments; Female; Hospitalization; Hospitalization - statistics & numerical data; Humans; Immunity; Immunization; Infant; Infants; Influenza; Influenza A; Influenza A Virus, H3N2 Subtype; Influenza B; Influenza B virus; Influenza vaccine; influenza vaccines; Influenza Vaccines - therapeutic use; Influenza, Human - prevention & control; Japan; Male; Maternal & child health; Odds Ratio; Patients; Repeated vaccination; Seasons; Test-negative case control design; Vaccination; Vaccine efficacy; Vaccines; Vaccines, Inactivated - therapeutic use; Viral infections; Japan; Hospitalization; Repeated vaccination; Effectiveness; Children; Test-negative case control design; Influenza vaccine

•Vaccine was effective in preventing illness, 38% against influenza A (mostly H3N2).•Vaccine was effective in preventing illness, 39% against influenza B.•Infants showed no significant vaccine effectiveness.•The children who were immunized in two consecutive seasons were more likely to have influenz...