Detection of early changes in the parahippocampal and posterior cingulum bundles during mild cognitive impairment by using high-resolution multi-parametric diffusion tensor imaging

• Published in: Psychiatry research. Neuroimaging Vol. 231; no. 3; pp. 346 - 352
• Main Authors: Ito, Kenji, Sasaki, Makoto, Takahashi, Junko, Uwano, Ikuko, Yamashita, Fumio, Higuchi, Satomi, Goodwin, Jonathan, Harada, Taisuke, Kudo, Kohsuke, Terayama, Yasuo
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier Ireland Ltd 30.03.2015
• Subjects: Aged; Aged, 80 and over; Alzheimer Disease - pathology; Alzheimer׳s disease; Anisotropy; Cognitive Dysfunction - pathology; Diffusion tensor imaging; Diffusion Tensor Imaging - methods; Female; Follow-Up Studies; Gyrus Cinguli - pathology; Humans; Male; Middle Aged; Mild cognitive impairment; Parahippocampal cingulum bundle; Posterior cingulum bundle; Psychiatry; Radiology; Single-Blind Method; Posterior cingulum bundle; Alzheimer׳s disease; Mild cognitive impairment; Parahippocampal cingulum bundle; Diffusion tensor imaging

Abstract We aimed to determine alterations occurring in the parahippocampal cingulum bundle (PhC) and posterior cingulum bundle (PoC) in patients with mild cognitive impairment (MCI) through analysis of high-resolution multi-parametric diffusion tensor imaging (DTI). Participants comprised 41 patien...