Detection of single-base DNA mutations by enzyme-amplified electronic transduction - Patolsky, Fernando; Lichtenstein, Amir; Willner, Itamar (Nature biotechnology, 2001)
Keywords: Agriculture; Alkaline Phosphatase - metabolism; Avidin - metabolism; Base Sequence; Bioinformatics; Biological and medical sciences; Biomedical and Life Sciences; Biomedical Engineering/Biotechnology; Biomedicine; Biosensors; Biotechnology; Biotinylation; Blood; Calibration; Chemical Precipitation; Deoxyribonucleic acid; Diverse techniques; DNA; DNA Mutational Analysis - methods; DNA-Directed DNA Polymerase - metabolism; Electric Conductivity; Electric Impedance; Electrodes; Enzymes - metabolism; Fundamental and applied biological sciences. Psychology; Humans; Impedance; Life Sciences; Methods. Procedures. Technologies; Molecular and cellular biology; Mutants; Mutation; Oligonucleotide Probes - genetics; Point Mutation - genetics; Polymorphism, Genetic - genetics; Quartz; Sensitivity and Specificity; Solubility; Spectroscopy; Tay-Sachs Disease - genetics; Various methods and equipments; Electrodes; Spectrometry; Biosensor; DNA; Point mutation; Faradaic impedance; Piezoelectric crystals; Method; Detection; Quartz microbalance