Combination analysis of neuropsychological tests and structural MRI measures in differentiating AD, MCI and control groups—The AddNeuroMed study

• Published in: Neurobiology of aging Vol. 32; no. 7; pp. 1198 - 1206
• Main Authors: Liu, Yawu, Paajanen, Teemu, Zhang, Yi, Westman, Eric, Wahlund, Lars-Olof, Simmons, Andrew, Tunnard, Catherine, Sobow, Tomasz, Mecocci, Patrizia, Tsolaki, Magda, Vellas, Bruno, Muehlboeck, Sebastian, Evans, Alan, Spenger, Christian, Lovestone, Simon, Soininen, Hilkka
• Format: Journal Article
• Language: English
• Published: London Elsevier Inc 01.07.2011; Elsevier
• Subjects: Aged; Aged, 80 and over; Alzheimer Disease - diagnosis; Alzheimer Disease - psychology; Alzheimer's disease; Biological and medical sciences; Cognition Disorders - diagnosis; Cognition Disorders - psychology; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Development. Senescence. Regeneration. Transplantation; Diagnosis, Differential; Female; Fundamental and applied biological sciences. Psychology; Hippocampus - pathology; Hippocampus - physiopathology; Humans; Internal Medicine; Longitudinal Studies; Male; MCI; Medical sciences; Mild cognitive impairment; MRI; Neurology; Neuropsychological Tests; Prospective Studies; Severity of Illness Index; Vertebrates: nervous system and sense organs; MCI; MRI; Mild cognitive impairment; Alzheimer's disease; Nervous system diseases; Senescence; Alzheimer disease; Central nervous system disease; Neuropsychological test; Degenerative disease; mild cognitive impairment; Nuclear magnetic resonance imaging; Cerebral disorder

To study the ability of neuropsychological tests, manual MRI hippocampal volume measures, regional volume and cortical thickness measures to identify subjects with Alzheimer's disease (AD), mild cognitive impairment (MCI), and healthy age-matched controls. Neuropsychological tests, manual hippo...