Three-season effectiveness of inactivated influenza vaccine in preventing influenza illness and hospitalization in children in Japan, 2013–2016

• Published in: Vaccine Vol. 36; no. 8; pp. 1063 - 1071
• Main Authors: Sugaya, Norio, Shinjoh, Masayoshi, Nakata, Yuji, Tsunematsu, Kenichiro, Yamaguchi, Yoshio, Komiyama, Osamu, Takahashi, Hiroki, Mitamura, Keiko, Narabayashi, Atsushi, Takahashi, Takao
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 14.02.2018; Elsevier Limited
• Subjects: Adolescents; Age; Age groups; Allergy and Immunology; Case studies; case-control studies; Child; Children; Children & youth; confidence interval; Confidence intervals; Diagnostic systems; Diagnostic tests; Effectiveness; Enrollments; Epidemics; Hospitalization; Hospitals; Illnesses; Immunization; Infants; Infectious diseases; Influenza; Influenza A; Influenza B; Influenza vaccine; influenza vaccines; Japan; Laboratories; Maternal & child health; Medical equipment; Orthomyxoviridae; Pediatrics; Seasons; Statistical analysis; Test-negative case control design; Vaccine efficacy; Vaccines; Viruses; United States > US; Texas; Japan; China; Hong Kong China; California; Thailand; Phuket Thailand; Hospitalization; Effectiveness; Test-negative case control design; Influenza vaccine; Child

•Three-season vaccine effectiveness in preventing influenza illness was 45% (N = 12,888).•Three-season vaccine effectiveness in preventing hospitalization was 52%.•Vaccine effectiveness was highest in young group and declined with age thereafter.•Low or no significant VE was demonstrated in infants...