Life-long in vivo cell-lineage tracing shows that no oogenesis originates from putative germline stem cells in adult mice - Zhang, Hua; Liu, Lian; Li, Xin; Busayavalasa, Kiran; Shen, Yan; Hovatta, Outi; Gustafsson, Jan-Åke; Liu, Kui (Proceedings of the National Academy of Sciences - PNAS, 2014)
Keywords: adult; Adult stem cells; Adult Stem Cells - cytology; adults; Analysis of Variance; animal cell; animal experiment; animal ovaries; animal tissue; Animals; Animals, Genetically Modified; Bacteria; Biological Sciences; Cancer and Oncology; Cancer och onkologi; Cell and Molecular Biology; cell lineage; Cell Lineage - physiology; Cell lines; Cell- och molekylärbiologi; controlled study; corpus luteum; cre recombinase; Crosses, Genetic; Female; Follicle tracing; Follicles; gene expression; Gene Expression Profiling; Genes; genetically engineered mouse strain; Genetically modified mouse models; Germ cells; germline stem cell; growth differentiation factor 9; Histological Techniques; Life span; Life-long observations; lifespan; male; messenger RNA; Mice; Mice, Mutant Strains; mouse; Mus; No postnatal oocyte regeneration; nonhuman; oocyte development; Oocyte tracing; Oocytes; Oocytes - physiology; Oogenesis; Oogenesis - physiology; Ovaries; ovary; primordial germ cell; regeneration; Reproduction; reverse transcription polymerase chain reaction; Rodents; somatic cell; Somatic cells; spermatogenesis; Stem cells; Tamoxifen; oocyte tracing; no postnatal oocyte regeneration; genetically modified mouse models; follicle tracing; life-long observations