Feasibility of a dried blood spot strategy for serological screening and surveillance to monitor elimination of Human African Trypanosomiasis in the Democratic Republic of the Congo

• Published in: PLoS neglected tropical diseases Vol. 15; no. 6; p. e0009407
• Main Authors: Inocencio da Luz, Raquel, Phanzu, Delphin Mavinga, Kiabanzawoko, Oscar N'lemvo, Miaka, Eric, Verlé, Paul, De Weggheleire, Anja, Büscher, Philippe, Hasker, Epco, Boelaert, Marleen
• Format: Journal Article
• Language: English
• Published: San Francisco Public Library of Science 01.06.2021; Public Library of Science (PLoS)
• Subjects: African trypanosomiasis; Antigens; Biology and Life Sciences; Blood; Control; Diagnosis; ELISA; Engineering and Technology; Enzyme-linked immunosorbent assay; Ethics; Feasibility; Feasibility studies; Filter paper; Health facilities; Health surveillance; Laboratories; Medicine and Health Sciences; Methods; People and Places; Public health; Quality control; Research and Analysis Methods; Samples; Sentinel health events; Serodiagnosis; Serology; Testing; Transmission; Tropical diseases; Trypanosomiasis; Vector-borne diseases; Congo (Kinshasa); Central Africa; Congo-Democratic Republic of Congo; Kongo

In recent years, the number of reported Human African Trypanosomiasis (HAT) cases caused by Trypanosoma brucei (T.b.) gambiense has been markedly declining, and the goal of 'elimination as a public health problem' is within reach. For the next stage, i.e. interruption of HAT transmission b...