The epidemic of Q fever in 2018 to 2019 in Zhuhai city of China determined by metagenomic next-generation sequencing

• Published in: PLoS neglected tropical diseases Vol. 15; no. 7; p. e0009520
• Main Authors: Huang, Mingxing, Ma, Jinmin, Jiao, Jun, Li, Chunna, Chen, Luan, Zhu, Zhongyi, Ruan, Feng, Xing, Li, Zheng, Xinchun, Fu, Mengjiao, Ma, Binyin, Gan, Chongjie, Mao, Yuanchen, Zhang, Chongnan, Sun, Ping, Liu, Xi, Lin, Ziliang, Chen, Lu, Lu, Zhiyu, Zhou, Dongsheng, Wen, Bohai, Chen, Weijun, Xiong, Xiaolu, Xia, Jinyu
• Format: Journal Article
• Language: English
• Published: San Francisco Public Library of Science 01.07.2021; Public Library of Science (PLoS)
• Subjects: Abattoirs; Biology and Life Sciences; Care and treatment; Cattle; Causes of; Cellular telephones; China; Deoxyribonucleic acid; Diagnosis; DNA; Engineering and Technology; Epidemics; Fever; Genetic aspects; Genomes; Genomic analysis; Genomics; Genotype; Health aspects; Identification and classification; Immunofluorescence; Infections; Infectious diseases; Influenza; Laboratories; Medicine and Health Sciences; Metagenomics; Next-generation sequencing; Nucleotide sequence; Outbreaks; Pathogens; Patients; PCR; Plasma; Polymerase chain reaction; Q fever; Samples; Sequencing; Strains; Tropical diseases; China; Beijing China; Australia; United States > US; Germany

Q fever is a worldwide zoonosis caused by Coxiella burnetii (Cb). From January 2018 to November 2019, plasma samples from 2,382 patients with acute fever of unknown cause at a hospital in Zhuhai city of China were tested using metagenomic next-generation sequencing (mNGS). Of those tested, 138 patie...